Epigenetics & Nuclear Signaling Antibodies 4

Anti-ZBTB48 Antibody (CAB7435)

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SKU:
CAB7435
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-ZBTB48 Antibody
Antibody SKU:CAB7435
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ZBTB48 (NP_005332.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:22Rv1, 293T, U-251MG, Mouse liver, Mouse testis, Mouse thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ZBTB48 (NP_005332.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDGS FVQH SVRV LQEL NKQR EKGQ YCDA TLDV GGLV FKAH WSVL ACCS HFFQ SLYG DGSG GSVV LPAG FAEI FGLL LDFF YTGH LALT SGNR DQVL LAAR ELRV PEAV ELCQ SFKP KTSV GQAA GGQS GLGP PASQ NVNS HVKE PAGL EEEE VSRT LGLV PRDQ EPRG SHSP QRPQ LHSP AQSE GPSS LCGK LKQA LKPC PLED KKPE DCKV PPRP LEAE GAQL QGGS NEWE VVVQ VEDD GDGD YMSE PEAV LTRR KSNV IRKP CAAE PALS AGSL AAEP
Gene ID:3104
Uniprot:P10074
Cellular Location:Nucleus
Calculated MW:77kDa
Observed MW:77kDa
Synonyms:ZBTB48, HKR3, TZAP, ZNF855, pp9964
Background:
UniProt Protein Function:ZBTB48: Binds to and regulates the J and/or S elements in MHC II promoter. Belongs to the krueppel C2H2-type zinc-finger protein family.
UniProt Protein Details:

Protein type:C2H2-type zinc finger protein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 1p36.3

Cellular Component: nucleoplasm; cytoplasm

Molecular Function:DNA binding; metal ion binding; transcription factor activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent

UniProt Code:P10074
NCBI GenInfo Identifier:1708212
NCBI Gene ID:3104
NCBI Accession:P10074.2
UniProt Secondary Accession:P10074,Q5SY19,
UniProt Related Accession:P10074
Molecular Weight:688
NCBI Full Name:Zinc finger and BTB domain-containing protein 48
NCBI Synonym Full Names:zinc finger and BTB domain containing 48
NCBI Official Symbol:ZBTB48  
NCBI Official Synonym Symbols:HKR3; ZNF855; pp9964  
NCBI Protein Information:zinc finger and BTB domain-containing protein 48; zinc finger protein 855; GLI-Kruppel family member HKR3; krueppel-related zinc finger protein 3
UniProt Protein Name:Zinc finger and BTB domain-containing protein 48
UniProt Synonym Protein Names:Krueppel-related zinc finger protein 3; Protein HKR3; Zinc finger protein 855
Protein Family:Zinc finger and BTB domain-containing protein
UniProt Gene Name:ZBTB48  
UniProt Entry Name:ZBT48_HUMAN
Anti-ZBTB48 Antibody (CAB7435)Western blot analysis of extracts of various cell lines, using ZBTB48 antibody (CAB7435) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-ZBTB48 Antibody (CAB7435)Immunohistochemistry of paraffin-embedded human brain cancer using ZBTB48 antibody (CAB7435) at dilution of 1:100 (40x lens).
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