Epigenetics & Nuclear Signaling Antibodies 3
Anti-YY2 Antibody (CAB16621)
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- SKU:
- CAB16621
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-YY2 Antibody |
| Antibody SKU: | CAB16621 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human YY2 (NP_996806.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human YY2 (NP_996806.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GEGQ AENP PDYS EYLK GKKL PPGG LPGI DLSD PKQL AEFT KVKP KRSK GEPP KTVP CSYS GCEK MFRD YAAM RKHL HIHG PRVH VCAE CGKA FLES SKLR R |
| Gene ID: | 404281 |
| Uniprot: | O15391 |
| Cellular Location: | Nucleus |
| Calculated MW: | 41kDa |
| Observed MW: | Refer to figures |
| Synonyms: | YY2, ZNF631 |
| Background: | The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. |
| UniProt Protein Function: | YY2: Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation. Belongs to the YY transcription factor family. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: Xp22.2-p22.1 |
| NCBI Summary: | The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010] |
| UniProt Code: | O15391 |
| NCBI GenInfo Identifier: | 74762100 |
| NCBI Gene ID: | 404281 |
| NCBI Accession: | O15391.1 |
| UniProt Secondary Accession: | O15391,Q6Q1S4, B2RP10, |
| UniProt Related Accession: | O15391 |
| Molecular Weight: | 41,347 Da |
| NCBI Full Name: | Transcription factor YY2 |
| NCBI Synonym Full Names: | YY2 transcription factor |
| NCBI Official Symbol: | YY2 |
| NCBI Official Synonym Symbols: | ZNF631 |
| NCBI Protein Information: | transcription factor YY2 |
| UniProt Protein Name: | Transcription factor YY2 |
| UniProt Synonym Protein Names: | Yin and yang 2; YY-2; Zinc finger protein 631 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | YY2 |
| UniProt Entry Name: | TYY2_HUMAN |
 | Western blot analysis of extracts of rat brain, using YY2 antibody (CAB16621) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Immunofluorescence analysis of NIH/3T3 cells using YY2 Rabbit pAb (CAB16621) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of HeLa cells using YY2 Rabbit pAb (CAB16621) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of C6 cells using YY2 Rabbit pAb (CAB16621) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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