Epigenetics & Nuclear Signaling Antibodies 1
Anti-YY1AP1 Antibody (CAB13104)
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- SKU:
- CAB13104
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-YY1AP1 Antibody |
| Antibody SKU: | CAB13104 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human YY1AP1 (NP_060723.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, BxPC-3, SGC-7901, HepG2, Mouse liver, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human YY1AP1 (NP_060723.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGFS NMED DGPE EEER VAEP QANF NTPQ ALRF EELL ANLL NEQH QIAK ELFE QLKM KKPS AKQQ KEVE KVKP QCKE VHQT |
| Gene ID: | 55249 |
| Uniprot: | Q9H869 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 50kDa/75-97kDa |
| Observed MW: | 88kDa |
| Synonyms: | YY1AP1, GRNG, HCCA1, HCCA2, YY1AP |
| Background: | The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | YY1AP1: Enhances transcription activation by YY1. May play a role in cell cycle regulation. 7 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1q22 Cellular Component: nucleus Molecular Function:protein binding Biological Process: regulation of cell cycle |
| NCBI Summary: | The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H869 |
| NCBI GenInfo Identifier: | 147744601 |
| NCBI Gene ID: | 55249 |
| NCBI Accession: | Q9H869.2 |
| UniProt Secondary Accession: | Q9H869,Q5VYZ1, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, B0QZ54 B4DMP2, B4E0I0, D3DV96, D3DV98, H7BY62, |
| UniProt Related Accession: | Q9H869 |
| Molecular Weight: | 97,716 Da |
| NCBI Full Name: | YY1-associated protein 1 |
| NCBI Synonym Full Names: | YY1 associated protein 1 |
| NCBI Official Symbol: | YY1AP1 |
| NCBI Official Synonym Symbols: | YAP; HCCA1; HCCA2; YY1AP |
| NCBI Protein Information: | YY1-associated protein 1 |
| UniProt Protein Name: | YY1-associated protein 1 |
| UniProt Synonym Protein Names: | Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated protein 2 |
| Protein Family: | YY1-associated protein |
| UniProt Gene Name: | YY1AP1 |
| UniProt Entry Name: | YYAP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using YY1AP1 antibody (CAB13104) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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