Cell Biology Antibodies 5
Anti-YWHAZ Antibody (CAB14797)
(No reviews yet)
Write a Review
- SKU:
- CAB14797
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-YWHAZ Antibody |
| Antibody SKU: | CAB14797 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human YWHAZ (NP_001129171.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human YWHAZ (NP_001129171.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDKN ELVQ KAKL AEQA ERYD DMAA CMKS VTEQ GAEL SNEE RNLL SVAY KNVV GARR SSWR VVSS IEQK TEGA EKKQ QMAR EYRE KIET ELRD ICND VLSL |
| Gene ID: | 7534 |
| Uniprot: | P63104 |
| Cellular Location: | Cytoplasm, Melanosome |
| Calculated MW: | 19kDa/27kDa |
| Observed MW: | Refer to figures |
| Synonyms: | YWHAZ, 14-3-3-zeta, HEL-S-3, HEL-S-93, HEL4, KCIP-1, YWHAD |
| Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. |
| UniProt Protein Function: | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. |
| NCBI Summary: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008] |
| UniProt Code: | P63104 |
| NCBI GenInfo Identifier: | 52000887 |
| NCBI Gene ID: | 7534 |
| NCBI Accession: | P63104.1 |
| UniProt Secondary Accession: | P63104,P29213, P29312, Q32P43, Q5XJ08, Q6GPI2, Q6IN74 Q6NUR9, Q6P3U9, Q86V33, A8K1N0, B7Z465, |
| UniProt Related Accession: | P63104 |
| Molecular Weight: | 19,333 Da |
| NCBI Full Name: | 14-3-3 protein zeta/delta |
| NCBI Synonym Full Names: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
| NCBI Official Symbol: | YWHAZ |
| NCBI Official Synonym Symbols: | HEL4; YWHAD; KCIP-1; HEL-S-3; HEL-S-93; 14-3-3-zeta |
| NCBI Protein Information: | 14-3-3 protein zeta/delta |
| UniProt Protein Name: | 14-3-3 protein zeta/delta |
| UniProt Synonym Protein Names: | Protein kinase C inhibitor protein 1; KCIP-1 |
| Protein Family: | 14-3-3 protein |
| UniProt Gene Name: | YWHAZ |
View AllClose
Related Products
