Epigenetics & Nuclear Signaling Antibodies 4
Anti-YTHDC1 Antibody (CAB7318)
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- SKU:
- CAB7318
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-YTHDC1 Antibody |
| Antibody SKU: | CAB7318 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-500 of human YTHDC1 (NP_001026902.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-500 of human YTHDC1 (NP_001026902.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EGND YDTR SEAS DSGS ESVS FTDG SVRS GSGT DGSD EKKK ERKR ARGI SPIV FDRS GSSA SESY AGSE KKHE KLSS SVRA VRKD QTSK LKYV LQDA RFFL IKSN NHEN VSLA KAKG VWST LPVN EKKL NLAF RSAR SVIL IFSV RESG KFQG FARL SSES HHGG SPIH WVLP AGMS AKML GGVF KIDW ICRR ELPF TKSA HLTN PWNE HKPV KIGR DGQE IELE CGTQ LCLL FPPD ESID L |
| Gene ID: | 91746 |
| Uniprot: | Q96MU7 |
| Cellular Location: | Nucleus |
| Calculated MW: | 82kDa/84kDa |
| Observed MW: | 118kDa |
| Synonyms: | YTHDC1, YT521, YT521-B |
| Background: |
| UniProt Protein Function: | YT521: May be part of a signal transduction pathway that influences splice site selection. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 4q13.2 Cellular Component: nuclear body; nucleus Molecular Function:protein binding; RNA binding Biological Process: mRNA splice site selection |
| UniProt Code: | Q96MU7 |
| NCBI GenInfo Identifier: | 47606762 |
| NCBI Gene ID: | 91746 |
| NCBI Accession: | Q96MU7.3 |
| UniProt Secondary Accession: | Q96MU7,Q4W5Q3, Q7Z622, Q8TF35, |
| UniProt Related Accession: | Q96MU7 |
| Molecular Weight: | 727 |
| NCBI Full Name: | YTH domain-containing protein 1 |
| NCBI Synonym Full Names: | YTH domain containing 1 |
| NCBI Official Symbol: | YTHDC1 |
| NCBI Official Synonym Symbols: | YT521; YT521-B |
| NCBI Protein Information: | YTH domain-containing protein 1; splicing factor YT521-B; putative splicing factor YT521 |
| UniProt Protein Name: | YTH domain-containing protein 1 |
| UniProt Synonym Protein Names: | Putative splicing factor YT521; YT521-B |
| Protein Family: | YTH domain-containing protein |
| UniProt Gene Name: | YTHDC1 |
| UniProt Entry Name: | YTDC1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using YTHDC1 antibody (CAB7318) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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