Epigenetics & Nuclear Signaling Antibodies 1
Anti-YAP1 Antibody (CAB11918)
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- SKU:
- CAB11918
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Fish - Zebrafish
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-YAP1 Antibody |
| Antibody SKU: | CAB11918 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF IP FC |
| Reactivity: | Human, Mouse, Zebrafish |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human YAP1 |
| Application: | WB IF IP FC |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:20 - 1:50 FC 1:20 - 1:50 |
| Reactivity: | Human, Mouse, Zebrafish |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant protein of human YAP1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10413 |
| Uniprot: | P46937 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa |
| Observed MW: | 65kDa |
| Synonyms: | COB1, YAP, YAP2, YAP65, YKI, YAP1 |
| Background: | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Code: | P46937 |
| NCBI GenInfo Identifier: | 294862479 |
| NCBI Gene ID: | 10413 |
| NCBI Accession: | P46937.2 |
| UniProt Secondary Accession: | P46937,Q7Z574, B4DTY1, B7ZA01, E3WEB5, E3WEB6, E9PRV2 F5H202, K0KQ18, K0KYZ8, K0L195, K0L1G3, |
| UniProt Related Accession: | P46937 |
| Molecular Weight: | 504 |
| NCBI Full Name: | Transcriptional coactivator YAP1 |
| NCBI Synonym Full Names: | Yes-associated protein 1 |
| NCBI Official Symbol: | YAP1 |
| NCBI Official Synonym Symbols: | YAP; YKI; COB1; YAP2; YAP65 |
| NCBI Protein Information: | transcriptional coactivator YAP1; yorkie homolog; protein yorkie homolog; yes-associated protein 2; 65 kDa Yes-associated protein; yes-associated protein YAP65 homolog |
| UniProt Protein Name: | Transcriptional coactivator YAP1 |
| UniProt Synonym Protein Names: | Protein yorkie homolog; Yes-associated protein YAP65 homolog |
| Protein Family: | Transcriptional coactivator |
| UniProt Gene Name: | YAP1 |
| UniProt Entry Name: | YAP1_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using YAP1 antibody (CAB11918). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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