Signal Transduction Antibodies 2

Anti-XPR1 Antibody (CAB16186)

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SKU:
CAB16186
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-XPR1 Antibody
Antibody SKU:CAB16186
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 464-631 of human XPR1 (NP_001129141.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 464-631 of human XPR1 (NP_001129141.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DLKM DWGL FDKN AGEN TFLR EEIV YPQK AYYY CAII EDVI LRFA WTIQ ISIT STTL LPHS GDII ATVF APLE VFRR FVWN FFRL ENEH LNNC GEFR AVRD ISVA PLNA DDQT LLEQ MMDQ DDGV RNRQ KNRS WKYN QSIS LRRP RLAS QSKA RDTK VLIE DTDD EANT
Gene ID:9213
Uniprot:Q9UBH6
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:73kDa/81kDa
Observed MW:Refer to figures
Synonyms:XPR1, IBGC6, SYG1, X3
Background:The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6.
UniProt Protein Function:XPR1: May function in G-protein coupled signal transduction. Potential receptor for xenotropic and polytropic murine leukemia retroviruses. Belongs to the SYG1 (TC 2.A.94) family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q25.1

Cellular Component: Golgi apparatus; integral to plasma membrane; plasma membrane

Molecular Function:G-protein coupled receptor activity; receptor activity; transmembrane receptor activity

Biological Process: cellular phosphate ion homeostasis; G-protein coupled receptor protein signaling pathway

Disease: Basal Ganglia Calcification, Idiopathic, 6

NCBI Summary:The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016]
UniProt Code:Q9UBH6
NCBI GenInfo Identifier:74753221
NCBI Gene ID:9213
NCBI Accession:Q9UBH6.1
UniProt Secondary Accession:Q9UBH6,O95719, Q7L8K9, Q8IW20, Q9NT19, Q9UFB9,
UniProt Related Accession:Q9UBH6
Molecular Weight:73,919 Da
NCBI Full Name:Xenotropic and polytropic retrovirus receptor 1
NCBI Synonym Full Names:xenotropic and polytropic retrovirus receptor 1
NCBI Official Symbol:XPR1  
NCBI Official Synonym Symbols:X3; SYG1; IBGC6  
NCBI Protein Information:xenotropic and polytropic retrovirus receptor 1
UniProt Protein Name:Xenotropic and polytropic retrovirus receptor 1
UniProt Synonym Protein Names:Protein SYG1 homolog; Xenotropic and polytropic murine leukemia virus receptor X3; X-receptor
Protein Family:Xenotropic and polytropic retrovirus receptor
UniProt Gene Name:XPR1  
UniProt Entry Name:XPR1_HUMAN
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