Anti-XCR1 Antibody (CAB20258)
- SKU:
- CAB20258
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GPR5
- Synonyms:
- CCXCR1
Description
| Product Name: | XCR1 Rabbit pAb |
| Product Code: | CAB20258 |
| Size: | 50uL, 100uL |
| Synonyms: | GPR5, CCXCR1 |
| Applications: | IHC |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human XCR1. |
| Applications: | IHC |
| Recommended Dilutions: | IHC 1:50 - 1:200 |
| Reactivity: | Rat |
| Immunogen: | Recombinant protein of human XCR1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2829 |
| Uniprot: | P46094 |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | XCR1: Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: integral to plasma membrane; plasma membrane Biological Process: elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; inflammatory response |
| NCBI Summary: | The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P46094 |
| NCBI GenInfo Identifier: | 1170008 |
| NCBI Gene ID: | 2829 |
| NCBI Accession: | P46094.1 |
| UniProt Related Accession: | P46094 |
| Molecular Weight: | 38,508 Da |
| NCBI Full Name: | Chemokine XC receptor 1 |
| NCBI Synonym Full Names: | X-C motif chemokine receptor 1 |
| NCBI Official Symbol: | XCR1 |
| NCBI Official Synonym Symbols: | GPR5; CCXCR1 |
| NCBI Protein Information: | chemokine XC receptor 1 |
| UniProt Protein Name: | Chemokine XC receptor 1 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1 |
| Protein Family: | Chemokine XC receptor |
| UniProt Gene Name: | XCR1 |
| UniProt Entry Name: | XCR1_HUMAN |
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