Signal Transduction Antibodies 1
Anti-WSB2 Antibody (CAB12970)
- SKU:
- CAB12970
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Antibody Name: | Anti-WSB2 Antibody |
Antibody SKU: | CAB12970 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human WSB2 (NP_061109.1). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse kidney, Rat kidney, Rat spleen |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human WSB2 (NP_061109.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MEAG EEPL LLAE LKPG RPHQ FDWK SSCE TWSV AFSP DGSW FAWS QGHC IVKL IPWP LEEQ FIPK GFEA KSRS SKNE TKGR GSPK EKTL DCGQ IVWG LAFS PWPS PPSR KLWA RHHP QVPD VSCL VLAT GLND GQIK IWEV QTGL LLLN LSGH QDVV RDLS FTPS GSLI LVSA SRDK TLRI WDLN KHGK QIQV LSGH LQWV |
Gene ID: | 55884 |
Uniprot: | Q9NYS7 |
Cellular Location: | |
Calculated MW: | 21kDa/45kDa/47kDa |
Observed MW: | 40-43kDa |
Synonyms: | WSB2, SBA2 |
Background: | This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | WSB2: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 12q24.23 |
NCBI Summary: | This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] |
UniProt Code: | Q9NYS7 |
NCBI GenInfo Identifier: | 20532294 |
NCBI Gene ID: | 55884 |
NCBI Accession: | Q9NYS7.1 |
UniProt Secondary Accession: | Q9NYS7,Q9NRX9, B4DIE6, B4DPV6, |
UniProt Related Accession: | Q9NYS7 |
Molecular Weight: | 21,809 Da |
NCBI Full Name: | WD repeat and SOCS box-containing protein 2 |
NCBI Synonym Full Names: | WD repeat and SOCS box containing 2 |
NCBI Official Symbol: | WSB2 |
NCBI Official Synonym Symbols: | SBA2 |
NCBI Protein Information: | WD repeat and SOCS box-containing protein 2 |
UniProt Protein Name: | WD repeat and SOCS box-containing protein 2 |
UniProt Synonym Protein Names: | CS box-containing WD protein |
Protein Family: | WD repeat and SOCS box-containing protein |
UniProt Gene Name: | WSB2 |
UniProt Entry Name: | WSB2_HUMAN |
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