Cell Biology Antibodies 13

Anti-WFDC1 Antibody (CAB17193)

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SKU:
CAB17193
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-WFDC1 Antibody
Antibody SKU:CAB17193
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 111-220 of human WFDC1 (NP_067020.2).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:293T, SGC-7901, Mouse brain, Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 111-220 of human WFDC1 (NP_067020.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PPVL DWLV QPKP RWLG GNGW LLDG PEEV LQAE ACST TEDG AEPL LCPS GYEC HILS PGDV AEGI PNRG QCVK QRRQ ADGR ILRH KLYK EYPE GDSK NVAE PGRG QQKH FQ
Gene ID:58189
Uniprot:Q9HC57
Cellular Location:
Calculated MW:
Observed MW:30kDa
Anti-WFDC1 Antibody (CAB17193)Western blot - WFDC1 Rabbit pAb (CAB17193)
Synonyms:WFDC1, PS20
Background:This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:WFDC1: Has growth inhibitory activity.
UniProt Protein Details:

Protein type:Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: extracellular space

Biological Process: regulation of cell growth

NCBI Summary:This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Code:Q9HC57
NCBI GenInfo Identifier:22096244
NCBI Gene ID:58189
NCBI Accession:Q9HC57.2
UniProt Secondary Accession:Q9HC57,Q8NC27, Q9HAU1, D3DUL7,
UniProt Related Accession:Q9HC57
Molecular Weight:23,977 Da
NCBI Full Name:WAP four-disulfide core domain protein 1
NCBI Synonym Full Names:WAP four-disulfide core domain 1
NCBI Official Symbol:WFDC1  
NCBI Official Synonym Symbols:PS20  
NCBI Protein Information:WAP four-disulfide core domain protein 1
UniProt Protein Name:WAP four-disulfide core domain protein 1
UniProt Synonym Protein Names:Prostate stromal protein ps20; ps20 growth inhibitor
Protein Family:WAP four-disulfide core domain protein
UniProt Gene Name:WFDC1  
UniProt Entry Name:WFDC1_HUMAN
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