Cell Biology Antibodies 6
Anti-WBSCR27 Antibody (CAB16176)
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- SKU:
- CAB16176
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-WBSCR27 Antibody |
| Antibody SKU: | CAB16176 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human WBSCR27 (NP_689772.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, MCF7, Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human WBSCR27 (NP_689772.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAQE EGGS LPEV RARV RAAH GIPD LAQK LHFY DRWA PDYD QDVA TLLY RAPR LAVD CLTQ ALPG PPHS ALIL DVAC GTGL VAAE LRAP GFLQ LHGV DGSP GMLE QAQA PGLY QRLS LCTL GQEP LPSP EGTF DAVL IVGA LSDG QVPC NAIP ELHV TKPG GLVC LTTR TNSS NLQY KEAL EATL DRLE QAGM WEGL VAWP VDRL WTAG SWLP PSWR WYPA SLPR MASS PALS TCTE SGRR PRLR K |
| Gene ID: | 155368 |
| Uniprot: | Q8N6F8 |
| Cellular Location: | |
| Calculated MW: | 26kDa |
| Observed MW: | 26kDa |
| Synonyms: | METTL27, WBSCR27 |
| Background: | This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. |
| UniProt Protein Function: | WBSCR27: WBSCR27 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR27 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. |
| UniProt Protein Details: | Protein type:Methyltransferase; Methyltransferase, protein arginine, predicted Chromosomal Location of Human Ortholog: 7q11.23 |
| NCBI Summary: | This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N6F8 |
| NCBI GenInfo Identifier: | 30795190 |
| NCBI Gene ID: | 155368 |
| NCBI Accession: | NP_689772.2 |
| UniProt Related Accession: | Q8N6F8 |
| Molecular Weight: | Calculated: 26kDaObserved: 26kDa |
| NCBI Full Name: | methyltransferase-like protein 27 |
| NCBI Synonym Full Names: | methyltransferase like 27 |
| NCBI Official Symbol: | METTL27 |
| NCBI Official Synonym Symbols: | WBSCR27 |
| NCBI Protein Information: | methyltransferase-like protein 27 |
| UniProt Protein Name: | Williams-Beuren syndrome chromosomal region 27 protein |
| Protein Family: | Williams-Beuren syndrome chromosomal region 27 protein |
| UniProt Gene Name: | WBSCR27 |
| UniProt Entry Name: | WBS27_HUMAN |
 | Western blot analysis of extracts of various cell lines, using WBSCR27 antibody (CAB16176) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Immunohistochemistry of paraffin-embedded Human colon using WBSCR27 Rabbit pAb (CAB16176) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Mouse brain using WBSCR27 Rabbit pAb (CAB16176) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Rat testis using WBSCR27 Rabbit pAb (CAB16176) at dilution of 1:50 (40x lens). |
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