Metabolism Antibodies 1

Anti-WARS2 Antibody (CAB15384)

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SKU:
CAB15384
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-WARS2 Antibody
Antibody SKU:CAB15384
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 211-360 of human WARS2 (NP_056651.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse brain, Mouse spleen, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 211-360 of human WARS2 (NP_056651.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LTSM KKVK SLRD PSAK MSKS DPDK LATV RITD SPEE IVQK FRKA VTDF TSEV TYDP AGRA GVSN IVAV HAAV TGLS VEEV VRRS AGMN TARY KLAV ADAV IEKF APIK REIE KLKL DKDH LEKV LQIG SAKA KELA YTVC QEVK KLVG FL
Gene ID:10352
Uniprot:Q9UGM6
Cellular Location:Mitochondrion matrix
Calculated MW:24kDa/40kDa
Observed MW:50kDa
Synonyms:WARS2, TrpRS
Background:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.
NCBI Summary:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Code:Q9UGM6
NCBI GenInfo Identifier:7710154
NCBI Gene ID:10352
NCBI Accession:NP_056651.1
UniProt Related Accession:Q9UGM6
Molecular Weight:
NCBI Full Name:tryptophan--tRNA ligase, mitochondrial isoform 1
NCBI Synonym Full Names:tryptophanyl tRNA synthetase 2, mitochondrial
NCBI Official Symbol:WARS2  
NCBI Official Synonym Symbols:TrpRS; NEMMLAS; mtTrpRS  
NCBI Protein Information:tryptophan--tRNA ligase, mitochondrial
UniProt Protein Name:Tryptophan--tRNA ligase, mitochondrial
UniProt Synonym Protein Names:(Mt)TrpRS; Tryptophanyl-tRNA synthetase; TrpRS
UniProt Gene Name:WARS2  
UniProt Entry Name:SYWM_HUMAN
Anti-WARS2 Antibody (CAB15384)Western blot analysis of extracts of various cell lines, using WARS2 antibody (CAB15384) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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