Cell Biology Antibodies 18
Anti-VPREB1 Antibody (CAB18391)
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- SKU:
- CAB18391
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-VPREB1 Antibody |
| Antibody SKU: | CAB18391 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human VPREB1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human VPREB1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7441 |
| Uniprot: | P12018 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | CD179a, IGI, IGVPB, VPREB, VPREB1 |
| Background: |
| UniProt Protein Function: | VPREB1: Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation. Belongs to the immunoglobulin superfamily. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 22q11.22 Cellular Component: extracellular space Biological Process: immune response; immunoglobulin production |
| NCBI Summary: | The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| UniProt Code: | P12018 |
| NCBI GenInfo Identifier: | 9911096 |
| NCBI Gene ID: | 7441 |
| NCBI Accession: | P12018.2 |
| UniProt Secondary Accession: | P12018,B5MCG2, |
| UniProt Related Accession: | P12018 |
| Molecular Weight: | 16,605 Da |
| NCBI Full Name: | Immunoglobulin iota chain |
| NCBI Synonym Full Names: | pre-B lymphocyte 1 |
| NCBI Official Symbol: | VPREB1 |
| NCBI Official Synonym Symbols: | IGI; IGVPB; VPREB; CD179a |
| NCBI Protein Information: | immunoglobulin iota chain |
| UniProt Protein Name: | Immunoglobulin iota chain |
| UniProt Synonym Protein Names: | CD179 antigen-like family member A; Protein VPreB1; V(pre)B protein; VpreB protein; CD_antigen: CD179a |
| Protein Family: | Immunoglobulin |
| UniProt Gene Name: | VPREB1 |
| UniProt Entry Name: | VPREB_HUMAN |
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