Cell Biology Antibodies 12
Anti-VNN2 Antibody (CAB8170)
- SKU:
- CAB8170
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | VNN2 Rabbit Polyclonal Antibody |
Antibody SKU: | CAB8170 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-493 of human VNN2 (NP_004656.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Raji, Mouse brain, Rat brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-493 of human VNN2 (NP_004656.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | VSLN MTGS GIYA PNGP KVYH YDMK TELG KLLL SEVD SHPL SSLA YPTA VNWN AYAT TIKP FPVQ KNTF RGFI SRDG FNFT ELFE NAGN LTVC QKEL CCHL SYRM LQKE ENEV YVLG AFTG LHGR RRRE YWQV CTML KCKT TNLT TCGR PVET ASTR FEMF SLSG TFGT EYVF PEVL LTEI HLSP GKFE VLKD GRLV NKNG SSGP ILTV SLFG RWYT KDSL YSSC |
Gene ID: | 8875 |
Uniprot: | O95498 |
Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
Calculated MW: | 13kDa/21kDa/33kDa/52kDa/58kDa |
Observed MW: | 33kDa |
Synonyms: | VNN2, FOAP-4, GPI-80, vanin 2 |
Background: | This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
UniProt Code: | O95498 |
NCBI GenInfo Identifier: | 17865816 |
NCBI Gene ID: | 8875 |
NCBI Accession: | NP_511043.1 |
UniProt Secondary Accession: | O95498,Q2XUN1, Q9UJF3, A0AUZ3, A6NDY1, A8K4E3, A8K7W0 B2DFZ0, B2DFZ1, B2DFZ2, B2DFZ3, F6XL73, |
UniProt Related Accession: | O95498 |
Molecular Weight: | 58,503 Da |
NCBI Full Name: | vascular non-inflammatory molecule 2 isoform 2 |
NCBI Synonym Full Names: | vanin 2 |
NCBI Official Symbol: | VNN2 |
NCBI Official Synonym Symbols: | FOAP-4; GPI-80 |
NCBI Protein Information: | vascular non-inflammatory molecule 2; vanin-2; Vannin 2; pantetheinase; glycosylphosphatidyl inositol-anchored protein GPI-80 |
UniProt Protein Name: | Vascular non-inflammatory molecule 2 |
UniProt Synonym Protein Names: | Glycosylphosphatidyl inositol-anchored protein GPI-80; Protein FOAP-4 |
Protein Family: | Vascular non-inflammatory molecule |
UniProt Gene Name: | VNN2 |
UniProt Entry Name: | VNN2_HUMAN |
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