Cell Biology Antibodies 11
Anti-VENTX Antibody (CAB7467)
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- SKU:
- CAB7467
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-VENTX Antibody |
| Antibody SKU: | CAB7467 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human VENTX (NP_055283.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, A-549, HepG2, SH-SY5Y, Mouse spinal cord, Rat bone marrow |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human VENTX (NP_055283.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MRLS SSPP RGPQ QLSS FGSV DWLS QSSC SGPT HTPR PADF SLGS LPGP GQTS GARE PPQA VSIK EAAG SSNL PAPE RTMA GLSK EPNT LRAP RVRT AFTM EQVR TLEG VFQH HQYL SPLE RKRL AREM QLSE VQIK TWFQ NRRM KHKR QMQD PQLH SPFS GSLH APPA FYST SSGL ANGL QLLC PWAP LSGP QALM LPPG SFWG LCQV AQEA LASA GASC CGQP LASH PPTP GRPS LGPA LSTG PRGL CAMP QTGD AF |
| Gene ID: | 27287 |
| Uniprot: | O95231 |
| Cellular Location: | Nucleus |
| Calculated MW: | 27kDa |
| Observed MW: | 28kDa |
| Synonyms: | VENTX, HPX42B, NA88A, VENTX2 |
| Background: | This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. |
| UniProt Protein Function: | VENTX: May be involved in ventralization. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 10q26.3 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding Biological Process: regulation of transcription, DNA-dependent; multicellular organismal development |
| NCBI Summary: | This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95231 |
| NCBI GenInfo Identifier: | 74762122 |
| NCBI Gene ID: | 27287 |
| NCBI Accession: | O95231.1 |
| UniProt Secondary Accession: | O95231,Q32MZ3, |
| UniProt Related Accession: | O95231 |
| Molecular Weight: | 258 |
| NCBI Full Name: | Homeobox protein VENTX |
| NCBI Synonym Full Names: | VENT homeobox |
| NCBI Official Symbol: | VENTX |
| NCBI Official Synonym Symbols: | NA88A; HPX42B; VENTX2 |
| NCBI Protein Information: | homeobox protein VENTX; VENT-like homeobox 2; VENT homeobox homolog; VENT-like homeobox protein 2; hemopoietic progenitor homeobox protein VENTX2 |
| UniProt Protein Name: | Homeobox protein VENTX |
| UniProt Synonym Protein Names: | VENT homeobox homolog; VENT-like homeobox protein 2 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | VENTX |
| UniProt Entry Name: | VENTX_HUMAN |
 | Western blot analysis of extracts of various cell lines, using VENTX antibody (CAB7467) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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