Cell Biology Antibodies 15
Anti-VDAC2 Antibody (CAB18683)
(No reviews yet)
Write a Review
- SKU:
- CAB18683
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-VDAC2 Antibody |
| Antibody SKU: | CAB18683 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VDAC2 (NP_003366.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, HepG2, HeLa, Mouse testis, Mouse kidney, Mouse brain, Rat kidney, Rat heart, Rat brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VDAC2 (NP_003366.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7417 |
| Uniprot: | P45880 |
| Cellular Location: | Mitochondrion outer membrane |
| Calculated MW: | 30kDa/31kDa/33kDa |
| Observed MW: | 30kDa |
 | Western blot - VDAC2 Rabbit pAb (CAB18683) |
| Synonyms: | VDAC2, POR, voltage dependent anion channel 2 |
| Background: | This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | VDAC2: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. Interacts with hexokinases. Expressed in all tissues examined. Belongs to the eukaryotic mitochondrial porin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Mitochondrial; Channel, misc. Chromosomal Location of Human Ortholog: 10q22 Cellular Component: pore complex; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; nucleus Molecular Function:protein binding; nucleotide binding; voltage-gated anion channel activity; porin activity Biological Process: negative regulation of protein polymerization; transmembrane transport; anion transport |
| NCBI Summary: | This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| UniProt Code: | P45880 |
| NCBI GenInfo Identifier: | 158518391 |
| NCBI Gene ID: | 7417 |
| NCBI Accession: | P45880.2 |
| UniProt Secondary Accession: | P45880,Q5VWK1, Q5VWK3, Q6IB40, Q7L3J5, Q9BWK8, Q9Y5I6 |
| UniProt Related Accession: | P45880 |
| Molecular Weight: | 294 |
| NCBI Full Name: | Voltage-dependent anion-selective channel protein 2 |
| NCBI Synonym Full Names: | voltage-dependent anion channel 2 |
| NCBI Official Symbol: | VDAC2 |
| NCBI Official Synonym Symbols: | POR |
| NCBI Protein Information: | voltage-dependent anion-selective channel protein 2; outer mitochondrial membrane protein porin 2 |
| UniProt Protein Name: | Voltage-dependent anion-selective channel protein 2 |
| UniProt Synonym Protein Names: | Outer mitochondrial membrane protein porin 2 |
| Protein Family: | Voltage-dependent anion-selective channel protein |
| UniProt Gene Name: | VDAC2 |
| UniProt Entry Name: | VDAC2_HUMAN |
Related Products
Anti-VDAC2 Antibody (CAB16294)
Cell Biology Antibodies 14
OverviewAntibody Name:Anti-VDAC2 Antibody (CAB16294)Antibody SKU:CAB16294Antibody Size:50µL, 100µLApplication:Western blottingReactivit
VDAC2 Monoclonal Antibody (CAB21260)
OverviewProduct Name:VDAC2 Monoclonal AntibodyProduct Code:CAB21260Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
VDAC2 Monoclonal Antibody (CAB22393)
VDAC2 Monoclonal Antibody (CAB22393)The product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
