Cell Biology Antibodies 14
Anti-VDAC2 Antibody (CAB16294)
- SKU:
- CAB16294
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
Antibody Name: | Anti-VDAC2 Antibody (CAB16294) |
Antibody SKU: | CAB16294 |
Antibody Size: | 50µL, 100µL |
Application: | Western blotting |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human VDAC2 (NP_001171712.1). |
Application: | Western blotting |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Mouse brain, Rat brain |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human VDAC2 (NP_001171712.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MSWC NELR LPAL KQHS IGRG LESH ITMC IPPS YADL GKAA RDIF NKGF GFGL VKLD VKTK SCSG VEFS TSGS SNTD TGKV TGTL ETKY KWCE YGLT FTEK WNTD NTLG TEIA IEDQ ICQG LKLT FDTT FSPN TGKK SGKI KSSY KREC INLG CDVD FDFA GPAI HGSA VFGY EGWL AGYQ MTFD SAKS KLTR NNFA VGYR TGDF QLHT NVND GTEF GGSI YQKV CEDL DTSV NLAW TSGT NCTR FGIA AKYQ LDPT ASIS AKVN NSSL IGVG YTQT LRPG VKLT LSAL VDGK SINA GGHK VGLA LELE A |
Cellular Location: | Mitochondrion outer membrane |
Calculated MW: | 30kDa/31kDa/33kDa |
Observed MW: | 31kDa |
Synonyms: | VDAC2, POR |
Background: | This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. |
Western blot analysis of extracts of various cell lines, using VDAC2 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s. |