Cell Biology Antibodies 9
Anti-UTP14A Antibody (CAB5960)
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- SKU:
- CAB5960
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-UTP14A Antibody |
| Antibody SKU: | CAB5960 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human UTP14A (NP_006640.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, A-549, NCI-H460, Mouse spleen, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human UTP14A (NP_006640.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTAN RLAE SLLA LSQQ EELA DLPK DYLL SESE DEGD NDGE RKHQ KLLE AISS LDGK NRRK LAER SEAS LKVS EFNV SSEG SGEK LVLA DLLE PVKT SSSL ATVK KQLS RVKS KKTV ELPL NKEE IERI HREV AFNK TAQV LSKW DPVV LKNR QAEQ LVFP LEKE EPAI APIE HVLS GWKA RTPL EQEI FNLL HKNK QPVT DPLL TPVE KASL RAMS LEEA KMRR AELQ RARA LQSY YEAK ARRE KKIK SKKY HKVV KKGK |
| Gene ID: | 10813 |
| Uniprot: | Q9BVJ6 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 69kDa/82kDa/87kDa |
| Observed MW: | 110kDa |
| Synonyms: | UTP14A, NYCO16, SDCCAG16, dJ537K23.3, Utp14 |
| Background: | This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | UTP14A: May be required for ribosome biogenesis. Belongs to the UTP14 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; RNA-binding; RNA processing Chromosomal Location of Human Ortholog: Xq26.1 Cellular Component: nucleolus; small subunit processome Molecular Function:protein binding Biological Process: rRNA processing |
| NCBI Summary: | This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9BVJ6 |
| NCBI GenInfo Identifier: | 68566226 |
| NCBI Gene ID: | 10813 |
| NCBI Accession: | Q9BVJ6.1 |
| UniProt Secondary Accession: | Q9BVJ6,Q5JYF1, A8K7A3, A8MVQ1, B4DQ08, E9PEL7, |
| UniProt Related Accession: | Q9BVJ6 |
| Molecular Weight: | 82,005 Da |
| NCBI Full Name: | U3 small nucleolar RNA-associated protein 14 homolog A |
| NCBI Synonym Full Names: | UTP14A small subunit processome component |
| NCBI Official Symbol: | UTP14A |
| NCBI Official Synonym Symbols: | NYCO16; SDCCAG16; dJ537K23.3 |
| NCBI Protein Information: | U3 small nucleolar RNA-associated protein 14 homolog A |
| UniProt Protein Name: | U3 small nucleolar RNA-associated protein 14 homolog A |
| UniProt Synonym Protein Names: | Antigen NY-CO-16; Serologically defined colon cancer antigen 16 |
| Protein Family: | U3 small nucleolar RNA-associated protein |
| UniProt Gene Name: | UTP14A |
| UniProt Entry Name: | UT14A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using UTP14A antibody (CAB5960) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded mouse brain using UTP14A antibody (CAB5960) at dilution of 1:100 (40x lens). |
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