Signal Transduction Antibodies 3

Anti-USP26 Antibody (CAB7999)

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SKU:
CAB7999
Product Type:
Antibody
Applications:
WB
Applications:
IF
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction

Description

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Antibody Name:USP26 Rabbit Polyclonal Antibody
Antibody SKU:CAB7999
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 664-913 of human USP26 (NP_114113.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, U-937, Mouse testis, Mouse liver, Mouse heart, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 664-913 of human USP26 (NP_114113.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TSLC QFHK AGGK PASS PGTP LSKV DFQT VPEN PKRK KYVK TSKF VAFD RIIN PTKD LYED KNIR IPER FQKV SEQT QQCD GMRI CEQA PQQA LPQS FPKP GTQG HTKN LLRP TKLN LQKS NRNS LLAL GSNK NPRN KDIL DKIK SKAK ETKR NDDK GDHT YRLI SVVS HLGK TLKS GHYI CDAY DFEK QIWF TYDD MRVL GIQE AQMQ EDRR CTGY IFFY MHNE IFEE MLKR EENA QLNS KEVE ETLQ KE
Gene ID:83844
Uniprot:Q9BXU7
Cellular Location:Nucleus
Calculated MW:104kDa
Observed MW:104kDa
Synonyms:USP26
Background:This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility.
UniProt Protein Function:USP26: Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway. Belongs to the peptidase C19 family.
UniProt Protein Details:

Protein type:Protease; EC 3.4.19.12; Ubiquitin conjugating system; Ubiquitin-specific protease

Chromosomal Location of Human Ortholog: Xq26.2

Cellular Component: nucleus

Molecular Function:protein binding

Biological Process: protein deubiquitination

Disease: Spermatogenic Failure, X-linked, 1

NCBI Summary:This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BXU7
NCBI GenInfo Identifier:13994268
NCBI Gene ID:83844
NCBI Accession:NP_114113.1
UniProt Secondary Accession:Q9BXU7,Q5H9H4, B9WRT6,
UniProt Related Accession:Q9BXU7
Molecular Weight:
NCBI Full Name:ubiquitin carboxyl-terminal hydrolase 26
NCBI Synonym Full Names:ubiquitin specific peptidase 26
NCBI Official Symbol:USP26  
NCBI Protein Information:ubiquitin carboxyl-terminal hydrolase 26
UniProt Protein Name:Ubiquitin carboxyl-terminal hydrolase 26
UniProt Synonym Protein Names:Deubiquitinating enzyme 26; Ubiquitin thioesterase 26; Ubiquitin-specific-processing protease 26
UniProt Gene Name:USP26  
UniProt Entry Name:UBP26_HUMAN
Anti-USP26 Polyclonal Antibody (CAB7999)Western blot analysis of extracts of various cell lines, using USP26 antibody (CAB7999) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-USP26 Polyclonal Antibody (CAB7999)Immunofluorescence analysis of A549 cells using USP26 antibody (CAB7999).
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