Autophagy Antibodies
Anti-USP10 Antibody (CAB4454)
- SKU:
- CAB4454
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- UBPO
- Research Area:
- Autophagy
Description
| Product Name: | USP10 Rabbit mAb |
| Product Code: | CAB4454 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | UBPO |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human USP10 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, 293T |
| Immunogen: | A synthesized peptide derived from human USP10 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9100 |
| Uniprot: | Q14694 |
| Calculated MW: | 110kDa |
| Observed MW: | 110KDa |
| UniProt Protein Function: | USP10: a carboxyl-terminal ubiquitin-processing protease. Ras-GAP SH3 domain-binding protein (G3BP) appears to inhibit its ability to disassemble ubiquitin chains. |
| UniProt Protein Details: | Protein type:Protease; Ubiquitin conjugating system; EC 3.4.19.12; RNA-binding; Ubiquitin-specific protease Chromosomal Location of Human Ortholog: 16q24.1 Cellular Component: cytoplasm; early endosome; nucleoplasm; nucleus Molecular Function:cysteine-type endopeptidase activity; p53 binding; protein binding; ubiquitin-specific protease activity Biological Process: bypass DNA synthesis; DNA damage response, signal transduction by p53 class mediator; protein deubiquitination; regulation of autophagy |
| NCBI Summary: | Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q14694 |
| NCBI GenInfo Identifier: | 2501458 |
| NCBI Gene ID: | 9100 |
| NCBI Accession: | Q14694.2 |
| UniProt Secondary Accession: | Q14694,Q9BWG7, Q9NSL7, B2RDJ8, B4DS84, |
| UniProt Related Accession: | Q14694 |
| Molecular Weight: | 87,533 Da |
| NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 10 |
| NCBI Synonym Full Names: | ubiquitin specific peptidase 10 |
| NCBI Official Symbol: | USP10 |
| NCBI Official Synonym Symbols: | UBPO |
| NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 10 |
| UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 10 |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme 10; Ubiquitin thioesterase 10; Ubiquitin-specific-processing protease 10 |
| UniProt Gene Name: | USP10 |
| UniProt Entry Name: | UBP10_HUMAN |
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