KO Validated Antibodies 2

Anti-UQCC2 Antibody (CAB19955)[KO Validated]

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SKU:
CAB19955
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-UQCC2 Antibody [KO Validated]
Antibody SKU:CAB19955
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human UQCC2.
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T
Immunogen:Recombinant protein of human UQCC2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:84300
Uniprot:Q9BRT2
Cellular Location:Mitochondrion, Mitochondrion inner membrane, Mitochondrion intermembrane space, Mitochondrion matrix, mitochondrion nucleoid
Calculated MW:14kDa
Observed MW:15KDa
Anti-UQCC2 Antibody [KO Validated] (CAB19955)Western blot analysis of extracts from normal (control) and UQCC2 knockout (KO) 293T cells, using UQCC2 antibody (CAB19955) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Synonyms:UQCC2, C6orf125, C6orf126, Cbp6, M19, MNF1, bA6B20.2
Background:This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity.
UniProt Protein Function:UQCC2: Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells
UniProt Protein Details:

Protein type:Mitochondrial

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nuclear body

Molecular Function:protein binding

Biological Process: regulation of insulin secretion; regulation of oxidative phosphorylation

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 7

NCBI Summary:This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]
UniProt Code:Q9BRT2
NCBI GenInfo Identifier:73917719
NCBI Gene ID:84300
NCBI Accession:Q9BRT2.1
UniProt Secondary Accession:Q9BRT2,B2R4I0,
UniProt Related Accession:Q9BRT2
Molecular Weight:15kDa
NCBI Full Name:Ubiquinol-cytochrome-c reductase complex assembly factor 2
NCBI Synonym Full Names:ubiquinol-cytochrome c reductase complex assembly factor 2
NCBI Official Symbol:UQCC2  
NCBI Official Synonym Symbols:M19; Cbp6; MNF1; C6orf125; C6orf126; bA6B20.2  
NCBI Protein Information:ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProt Protein Name:Ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProt Synonym Protein Names:Breast cancer-associated protein SGA-81M; Mitochondrial nucleoid factor 1; Mitochondrial protein M19
Protein Family:Ubiquinol-cytochrome-c reductase complex assembly factor
UniProt Gene Name:UQCC2  
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