Cell Biology Antibodies 11

Anti-UGT2B10 Antibody (CAB7570)

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SKU:
CAB7570
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-UGT2B10 Antibody
Antibody SKU:CAB7570
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human UGT2B10 (NP_001066.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, SKOV3, U-937, Mouse liver, Mouse kidney, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human UGT2B10 (NP_001066.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GSCG KVLV WAAE YSLW MNMK TILK ELVQ RGHE VTVL ASSA SILF DPND SSTL KLEV YPTS LTKT EFEN IIMQ LVKR LSEI QKDT FWLP FSQE QEIL WAIN DIIR NFCK DVVS NKKL MKKL QESR FDIV FADA YLPC GELL AELF NIPF VYSH SFSP GYSF ERHS GGFI FPPS YVPV VMSK LSDQ MTFM ERVK NMLY VLYF DFWF QIFN MKKW DQFY SEVL GRPT TLSE TMRK ADIW LMRN SWNF KFPH PFLP NVDF VGGL H
Gene ID:7365
Uniprot:P36537
Cellular Location:Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein
Calculated MW:50kDa/60kDa
Observed MW:65kDa/80kDa
Synonyms:UGT2B10, UDPGT2B10
Background:
UniProt Protein Function:UGT2B10: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family.
UniProt Protein Details:

Protein type:Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Xenobiotic Metabolism - drug metabolism - other enzymes; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - starch and sucrose; Membrane protein, integral; Carbohydrate Metabolism - ascorbate and aldarate; Lipid Metabolism - androgen and estrogen; Cofactor and Vitamin Metabolism - retinol; EC 2.4.1.17; Xenobiotic Metabolism - metabolism by cytochrome P450; Transferase

Chromosomal Location of Human Ortholog: 4q13.2

Cellular Component: intracellular membrane-bound organelle

Molecular Function:glucuronosyltransferase activity

Biological Process: flavonoid biosynthetic process; lipid metabolic process

UniProt Code:P36537
NCBI GenInfo Identifier:549155
NCBI Gene ID:7365
NCBI Accession:P36537.1
UniProt Secondary Accession:P36537,Q14CR8, A8K9M3, B4DPP1,
UniProt Related Accession:P36537
Molecular Weight:50,688 Da
NCBI Full Name:UDP-glucuronosyltransferase 2B10
NCBI Synonym Full Names:UDP glucuronosyltransferase family 2 member B10
NCBI Official Symbol:UGT2B10  
NCBI Official Synonym Symbols:UDPGT2B10  
NCBI Protein Information:UDP-glucuronosyltransferase 2B10
UniProt Protein Name:UDP-glucuronosyltransferase 2B10
Protein Family:UDP-glucuronosyltransferase
UniProt Gene Name:UGT2B10  
UniProt Entry Name:UDB10_HUMAN
Anti-UGT2B10 Antibody (CAB7570)Western blot analysis of extracts of various cell lines, using UGT2B10 antibody (CAB7570) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-UGT2B10 Antibody (CAB7570)Immunohistochemistry of paraffin-embedded human liver damage using UGT2B10 antibody (CAB7570) at dilution of 1:100 (40x lens).
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