Signal Transduction Antibodies 2
Anti-UBR7 Antibody (CAB15464)
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- SKU:
- CAB15464
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-UBR7 Antibody |
| Antibody SKU: | CAB15464 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 76-425 of human UBR7 (NP_786924.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Jurkat, Mouse thymus, Mouse testis, Rat thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 76-425 of human UBR7 (NP_786924.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LACS YECH GSHK LFEL YTKR NFRC DCGN SKFK NLEC KLLP DKAK VNSG NKYN DNFF GLYC ICKR PYPD PEDE IPDE MIQC VVCE DWFH GRHL GAIP PESG DFQE MVCQ ACMK RCSF LWAY AAQL AVTK ISTE DDGL VRNI DGIG DQEV IKPE NGEH QDST LKED VPEQ GKDD VREV KVEQ NSEP CAGS SSES DLQT VFKN ESLN AESK SGCK LQEL KAKQ LIKK DTAT YWPL NWRS KLCT CQDC MKMY GDLD VLFL TDEY DTVL AYEN KGKI AQAT DRSD PLMD TLSS MNRV QQVE LICE YNDL KTEL KDYL KRFA DEGT VVKR EDIQ QFFE EFQS KKRR RVDG MQYY CS |
| Gene ID: | 55148 |
| Uniprot: | Q8N806 |
| Cellular Location: | |
| Calculated MW: | 47kDa |
| Observed MW: | 50kDa |
| Synonyms: | UBR7, C14orf130 |
| Background: | This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. |
| UniProt Code: | Q8N806 |
| NCBI GenInfo Identifier: | 37999713 |
| NCBI Gene ID: | 55148 |
| NCBI Accession: | Q8N806.2 |
| UniProt Secondary Accession: | Q8N806,Q86U21, Q86UA9, Q96BY0, Q9NVV6, |
| UniProt Related Accession: | Q8N806 |
| Molecular Weight: | 425 |
| NCBI Full Name: | Putative E3 ubiquitin-protein ligase UBR7 |
| NCBI Synonym Full Names: | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
| NCBI Official Symbol: | UBR7 |
| NCBI Official Synonym Symbols: | C14orf130 |
| NCBI Protein Information: | putative E3 ubiquitin-protein ligase UBR7; N-recognin-7 |
| UniProt Protein Name: | Putative E3 ubiquitin-protein ligase UBR7 |
| UniProt Synonym Protein Names: | N-recognin-7 |
| Protein Family: | Putative E3 ubiquitin-protein ligase |
| UniProt Gene Name: | UBR7 |
| UniProt Entry Name: | UBR7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using UBR7 antibody (CAB15464) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Western blot analysis of extracts of various cell lines, using UBR7 antibody (CAB15464) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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