Autophagy Antibodies
Anti-UBQLN4 Antibody (CAB15869)
- SKU:
- CAB15869
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Description
| Antibody Name: | Anti-UBQLN4 Antibody |
| Antibody SKU: | CAB15869 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-390 of human UBQLN4 (NP_064516.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-390 of human UBQLN4 (NP_064516.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QFGN NPFS SLAG NSDS SSSQ PLRT ENRE PLPN PWSP SPPT SQAP GSGG EGTG GSGT SQVH PTVS NPFG INAA SLGS GMFN SPEM QALL QQI |
| Gene ID: | 56893 |
| Uniprot: | Q9NRR5 |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Nucleus, autophagosome, perinuclear region |
| Calculated MW: | 24kDa/63kDa |
| Observed MW: | 75kDa |
| Synonyms: | UBQLN4, A1U, A1Up, C1orf6, CIP75, UBIN |
| Background: |
| UniProt Protein Function: | UBQLN4: Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: endoplasmic reticulum membrane; perinuclear region of cytoplasm; cytoplasm; cytosol; nucleus Molecular Function:identical protein binding; protein binding; polyubiquitin binding Biological Process: regulation of proteasomal ubiquitin-dependent protein catabolic process |
| UniProt Code: | Q9NRR5 |
| NCBI GenInfo Identifier: | 45476982 |
| NCBI Gene ID: | 56893 |
| NCBI Accession: | Q9NRR5.2 |
| UniProt Secondary Accession: | Q9NRR5,Q5VYA0, Q5VYA1, Q9BR98, Q9UHX4, A6ND44, B2RAY7 |
| UniProt Related Accession: | Q9NRR5 |
| Molecular Weight: | 24,527 Da |
| NCBI Full Name: | Ubiquilin-4 |
| NCBI Synonym Full Names: | ubiquilin 4 |
| NCBI Official Symbol: | UBQLN4 |
| NCBI Official Synonym Symbols: | A1U; A1Up; UBIN; CIP75; C1orf6 |
| NCBI Protein Information: | ubiquilin-4; connexin43-interacting protein of 75 kDa; ataxin-1 interacting ubiquitin-like protein; ataxin-1 ubiquitin-like interacting protein; ataxin-1 ubiquitin-like-interacting protein A1U |
| UniProt Protein Name: | Ubiquilin-4 |
| UniProt Synonym Protein Names: | Ataxin-1 interacting ubiquitin-like protein; A1Up; Ataxin-1 ubiquitin-like-interacting protein A1U; Connexin43-interacting protein of 75 kDa; CIP75 |
| UniProt Gene Name: | UBQLN4 |
| UniProt Entry Name: | UBQL4_HUMAN |
 | Western blot analysis of extracts of 293T cells, using UBQLN4 antibody (CAB15869) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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