Cell Biology Antibodies 13

Anti-UBQLN3 Antibody (CAB17697)

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SKU:
CAB17697
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-UBQLN3 Antibody
Antibody SKU:CAB17697
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:PC-3, Mouse testis, Rat testis, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:WTST HGGS GSRQ GRQD GDQD APDI RNRF PNFL GIIR LYDY LQQL HENP QSLG TYLQ GTAS ALSQ SQEP PPSV NRVP PSSP SSQE PGSG QPLP EESV AIKG RSSC PAFL RYPT ENST GQGG DQDG AGKS STGH STNL PDLV SGLG DSAN RVPF APLS FSPT AAIP GIPE PPWL PSPA YPRS LRPD GMNP APQL QDEI QPQL PLLM HLQA AMAN PRAL QALR QIEQ GLQV LATE APRL LLWF MPCL AGTG SVAG GIES REDP LMSE DPLP NPPP EVFP ALDS AELG FLSP PFLH MLQD LVST NPQQ LQPE AHFQ VQL
Gene ID:50613
Uniprot:Q9H347
Cellular Location:
Calculated MW:70kDa
Observed MW:71kDa
Anti-UBQLN3 Antibody (CAB17697)Western blot - UBQLN3 Polyclonal Antibody (CAB17697)
Synonyms:TUP-1, UBQLN3
Background:This gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis. It has been suggested that this gene may regulate cell-cycle progression during spermatogenesis, however, it has been shown that the ortholgous mouse gene is dispensable for embryonic development and spermatogenesis. [provided by RefSeq, Nov 2016]
UniProt Protein Function:UBQLN3:
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 11p15

NCBI Summary:Summary: This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis. [provided by RefSeq, Jul 2008]
UniProt Code:Q9H347
NCBI GenInfo Identifier:8567418
NCBI Gene ID:50613
NCBI Accession:NP_059509.1
UniProt Secondary Accession:Q9H347,Q9NRE0,
UniProt Related Accession:Q9H347
Molecular Weight:70,841 Da
NCBI Full Name:ubiquilin-3
NCBI Synonym Full Names:ubiquilin 3
NCBI Official Symbol:UBQLN3  
NCBI Official Synonym Symbols:TUP-1  
NCBI Protein Information:ubiquilin-3
UniProt Protein Name:Ubiquilin-3
Protein Family:Ubiquilin
UniProt Gene Name:UBQLN3  
UniProt Entry Name:UBQL3_HUMAN
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