Name: Anti-UBE2G1 Antibody (CAB6997)
Brand: Signal Transduction Antibodies 3
SKU: CAB6997
Availability: OutOfStock

Antibody Name:	Anti-UBE2G1 Antibody
Antibody SKU:	CAB6997
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human UBE2G1 (NP_003333.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human UBE2G1 (NP_003333.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MTEL QSAL LLRR QLAE LNKN PVEG FSAG LIDD NDLY RWEV LIIG PPDT LYEG GVFK AHLT FPKD YPLR PPKM KFIT EIWH PNVD KNGD VCIS ILHE PGED KYGY EKPE ERWL PIHT VETI MISV ISML ADPN GDSP ANVD AAKE WRED RNGE FKRK VARC VRKS QETA FE
Gene ID:	7326
Uniprot:	P62253
Cellular Location:
Calculated MW:	19kDa
Observed MW:	Refer to figures

Synonyms:

UBE2G1, E217K, UBC7, UBE2G

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins.

UniProt Protein Function:	UBE2G1: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4. Belongs to the ubiquitin-conjugating enzyme family.
UniProt Protein Details:	Protein type:EC 6.3.2.19; Ligase; Ubiquitin ligase; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 17p13.2 Cellular Component: cytoplasm Molecular Function:small conjugating protein ligase activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding; ligase activity Biological Process: ubiquitin-dependent protein catabolic process; cellular protein catabolic process
NCBI Summary:	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]
UniProt Code:	P62253
NCBI GenInfo Identifier:	51338681
NCBI Gene ID:	7326
NCBI Accession:	P62253.3
UniProt Secondary Accession:	P62253,Q99462, B2R7P2, D3DTK0,
UniProt Related Accession:	P62253
Molecular Weight:	170
NCBI Full Name:	Ubiquitin-conjugating enzyme E2 G1
NCBI Synonym Full Names:	ubiquitin-conjugating enzyme E2G 1
NCBI Official Symbol:	UBE2G1
NCBI Official Synonym Symbols:	UBC7; E217K; UBE2G
NCBI Protein Information:	ubiquitin-conjugating enzyme E2 G1; ubiquitin-protein ligase G1; ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7)
UniProt Protein Name:	Ubiquitin-conjugating enzyme E2 G1
UniProt Synonym Protein Names:	E217K; UBC7; Ubiquitin carrier protein G1; Ubiquitin-protein ligase G1Ubiquitin-conjugating enzyme E2 G1, N-terminally processed
Protein Family:	Ubiquitin-conjugating enzyme
UniProt Gene Name:	UBE2G1
UniProt Entry Name:	UB2G1_HUMAN