Cell Biology Antibodies 15
Anti-UBE2E3 Antibody (CAB18652)
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- SKU:
- CAB18652
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-UBE2E3 Antibody |
| Antibody SKU: | CAB18652 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human UBE2E3. |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant protein of human UBE2E3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10477 |
| Uniprot: | Q969T4 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | |
| Background: |
| UniProt Protein Function: | UBE2E3: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. Belongs to the ubiquitin-conjugating enzyme family. |
| UniProt Protein Details: | Protein type:EC 6.3.2.19; Ubiquitin ligase; Ubiquitin conjugating system; Ligase Chromosomal Location of Human Ortholog: 2q32.1 Molecular Function:protein binding; ubiquitin-protein ligase activity |
| NCBI Summary: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q969T4 |
| NCBI GenInfo Identifier: | 47606197 |
| NCBI Gene ID: | 10477 |
| NCBI Accession: | Q969T4.1 |
| UniProt Secondary Accession: | Q969T4,Q5U0R7, Q7Z4W4, B2RAD6, D3DPG3, |
| UniProt Related Accession: | Q969T4 |
| Molecular Weight: | 22,913 Da |
| NCBI Full Name: | Ubiquitin-conjugating enzyme E2 E3 |
| NCBI Synonym Full Names: | ubiquitin conjugating enzyme E2 E3 |
| NCBI Official Symbol: | UBE2E3 |
| NCBI Official Synonym Symbols: | UBCH9; UbcM2 |
| NCBI Protein Information: | ubiquitin-conjugating enzyme E2 E3 |
| UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 E3 |
| UniProt Synonym Protein Names: | E2 ubiquitin-conjugating enzyme E3; UbcH9; Ubiquitin carrier protein E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3 |
| Protein Family: | Ubiquitin-conjugating enzyme |
| UniProt Gene Name: | UBE2E3 |
| UniProt Entry Name: | UB2E3_HUMAN |
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