Cell Biology Antibodies 14

Anti-UBE2E1 Antibody (CAB13912)

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SKU:
CAB13912
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-UBE2E1 Antibody
Antibody SKU:CAB13912
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human UBE2E1 (NP_003332.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, HeLa, K-562
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human UBE2E1 (NP_003332.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSDD DSRA STSS SSSS SSNQ QTEK ETNT PKKK ESKV SMSK NSKL LSTS AKRI QKEL ADIT LDPP PNCS AGPK GDNI YEWR STIL GPPG SVYE GGVF FLDI TFTP EYPF KPPK VTFR TRIY HCNI NSQG VICL DILK DNWS PALT ISKV LLSI CSLL TDCN PADP LVGS IATQ YMTN RAEH DRMA RQWT KRYA T
Gene ID:7324
Uniprot:P51965
Cellular Location:Nucleus
Calculated MW:Refer to figures
Observed MW:21kDa
Anti-UBE2E1 AntibodyWestern blot - UBE2E1 Rabbit pAb (CAB13912)
Synonyms:UBE2E1, UBCH6
Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UniProt Protein Function:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.
NCBI Summary:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
UniProt Code:P51965
NCBI GenInfo Identifier:4507779
NCBI Gene ID:7324
NCBI Accession:NP_003332.1
UniProt Secondary Accession:P51965,B2RBX4, C9J8K2, K4DI90,
UniProt Related Accession:P51965
Molecular Weight:19,499 Da
NCBI Full Name:ubiquitin-conjugating enzyme E2 E1 isoform 1
NCBI Synonym Full Names:ubiquitin conjugating enzyme E2 E1
NCBI Official Symbol:UBE2E1  
NCBI Official Synonym Symbols:UBCH6  
NCBI Protein Information:ubiquitin-conjugating enzyme E2 E1
UniProt Protein Name:Ubiquitin-conjugating enzyme E2 E1
UniProt Synonym Protein Names:(E3-independent) E2 ubiquitin-conjugating enzyme E1 (EC:2.3.2.24
Protein Family:Ubiquitin-conjugating enzyme
UniProt Gene Name:UBE2E1  
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