Signal Transduction Antibodies 1

Anti-UBAC1 Antibody (CAB13071)

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SKU:
CAB13071
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-UBAC1 Antibody
Antibody SKU:CAB13071
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 176-405 of human UBAC1 (NP_057256.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, Mouse liver, Mouse lung, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 176-405 of human UBAC1 (NP_057256.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LFKK ANAM LDED EDER VDEA ALRQ LTEM GFPE NRAT KALQ LNHM SVPQ AMEW LIEH AEDP TIDT PLPG QAPP EAEG ATAA ASEA AAGA SATD EEAR DELT EIFK KIRR KREF RADA RAVI SLME MGFD EKEV IDAL RVNN NQQN AACE WLLG DRKP SPEE LDKG IDPD SPLF QAIL DNPV VQLG LTNP KTLL AFED MLEN PLNS TQWM NDPE TGPV MLQI SRIF QTLN RT
Gene ID:10422
Uniprot:Q9BSL1
Cellular Location:Cytoplasm
Calculated MW:45kDa
Observed MW:45kDa
Synonyms:UBAC1, GBDR1, KPC2, UBADC1
Background:
UniProt Protein Function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
UniProt Code:Q9BSL1
NCBI GenInfo Identifier:55770884
NCBI Gene ID:10422
NCBI Accession:NP_057256.2
UniProt Secondary Accession:Q9BSL1,O75500, Q9UMW7,
UniProt Related Accession:Q9BSL1
Molecular Weight:45,338 Da
NCBI Full Name:ubiquitin-associated domain-containing protein 1
NCBI Synonym Full Names:UBA domain containing 1
NCBI Official Symbol:UBAC1  
NCBI Official Synonym Symbols:KPC2; GBDR1; UBADC1  
NCBI Protein Information:ubiquitin-associated domain-containing protein 1
UniProt Protein Name:Ubiquitin-associated domain-containing protein 1
UniProt Synonym Protein Names:E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting complex protein 2
UniProt Gene Name:UBAC1  
Anti-UBAC1 Antibody (CAB13071)Western blot analysis of extracts of various cell lines, using UBAC1 antibody (CAB13071) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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