Anti-UAP1 Antibody (CAB8662)
- SKU:
- CAB8662
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AGX
- Synonyms:
- AGX1
- Synonyms:
- AGX2
- Synonyms:
- SPAG2
- Research Area:
- Cell Biology
Description
| Product Name: | UAP1 Rabbit mAb |
| Product Code: | CAB8662 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AGX, AGX1, AGX2, SPAG2 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human UAP1 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, DU145, Jurkat, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human UAP1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6675 |
| Uniprot: | Q16222 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 59kDa |
| Observed MW: | 59kDa |
| UniProt Protein Function: | UAP1: Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. Belongs to the UDPGP type 1 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transferase; EC 2.7.7.23; EC 2.7.7.83; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q23.3 Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol Molecular Function:UDP-N-acetylglucosamine diphosphorylase activity; carbohydrate binding Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; UDP-N-acetylglucosamine biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
| UniProt Code: | Q16222 |
| NCBI GenInfo Identifier: | 68846235 |
| NCBI Gene ID: | 6675 |
| NCBI Accession: | Q16222.3 |
| UniProt Secondary Accession: | Q16222,Q91YN5, |
| UniProt Related Accession: | Q16222 |
| Molecular Weight: | |
| NCBI Full Name: | UDP-N-acetylhexosamine pyrophosphorylase |
| NCBI Synonym Full Names: | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| NCBI Official Symbol: | UAP1 |
| NCBI Official Synonym Symbols: | AGX; AGX1; AGX2; SPAG2 |
| NCBI Protein Information: | UDP-N-acetylhexosamine pyrophosphorylase |
| UniProt Protein Name: | UDP-N-acetylhexosamine pyrophosphorylase |
| UniProt Synonym Protein Names: | Antigen X; AGX; Sperm-associated antigen 2Including the following 2 domains:UDP-N-acetylgalactosamine pyrophosphorylase (EC:2.7.7.83)Alternative name(s):AGX-1 |
| Protein Family: | UDP-N-acetylhexosamine pyrophosphorylase |
| UniProt Gene Name: | UAP1 |
| UniProt Entry Name: | UAP1_HUMAN |
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