Cell Cycle Antibodies 1

Anti-TXNL4A Antibody (CAB10138)

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SKU:
CAB10138
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TXNL4A Antibody
Antibody SKU:CAB10138
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:LO2, HeLa, Jurkat, HL-60, Mouse pancreas, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human TXNL4A (NP_006692.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSYM LPHL HNGW QVDQ AILS EEDR VVVI RFGH DWDP TCMK MDEV LYSI AEKV KNFA VIYL VDIT EVPD FNKM YELY DPCT VMFF FRNK HIMI DLGT GNNN KINW AMED KQEM VDII ETVY RGAR KGRG LVVS PKDY STKY RY
Gene ID:10907
Uniprot:P83876
Cellular Location:Nucleus
Calculated MW:16kDa
Observed MW:13kDa
Synonyms:TXNL4A, BMKS, DIB1, DIM1, SNRNP15, TXNL4, U5-15kD
Background:The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants.
NCBI Summary:The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
UniProt Code:P83876
NCBI GenInfo Identifier:33875918
NCBI Gene ID:10907
NCBI Accession:BC001046
UniProt Secondary Accession:P83876,O14834, B2RC18,
UniProt Related Accession:P83876
Molecular Weight:16,786 Da
NCBI Full Name:Homo sapiens thioredoxin-like 4A, mRNA
NCBI Synonym Full Names:thioredoxin like 4A
NCBI Official Symbol:TXNL4A  
NCBI Official Synonym Symbols:BMKS; DIB1; DIM1; TXNL4; SNRNP15; U5-15kD  
NCBI Protein Information:thioredoxin-like protein 4A
UniProt Protein Name:
Protein Family:Thioredoxin-like protein
UniProt Gene Name:
Anti-TXNL4A Antibody (CAB10138)Western blot analysis of extracts of various cell lines, using TXNL4A antibody (CAB10138) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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