Cell Cycle Antibodies 1

Anti-TXLNG Antibody (CAB15865)

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SKU:
CAB15865
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-TXLNG Antibody
Antibody SKU:CAB15865
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TXLNG (NP_060830.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, A-549
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TXLNG (NP_060830.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATR VEEA ARGR GGGA EEAT EAGR GGRR RSPR QKFE IGTM EEAG ICGL GVKA DMLC NSQS NDIL QHQG SNCG GTSN KHSL EEDE GSDF ITEN RNLV SPAY CTQE SREE IPGG EART DPPD GQQD SECN RNKE KTLG KEVL
Gene ID:55787
Uniprot:Q9NUQ3
Cellular Location:Cytoplasm, Nucleus membrane, cytosol
Calculated MW:46kDa/60kDa
Observed MW:75kDa
Synonyms:TXLNG, CXorf15, ELRG, FIAT, LSR5, TXLNGX
Background:This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Summary:This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
UniProt Code:Q9NUQ3
NCBI GenInfo Identifier:281182404
NCBI Gene ID:55787
NCBI Accession:NP_060830.2
UniProt Related Accession:Q9NUQ3
Molecular Weight:75kDa
NCBI Full Name:gamma-taxilin isoform 1
NCBI Synonym Full Names:taxilin gamma
NCBI Official Symbol:TXLNG  
NCBI Official Synonym Symbols:ELRG; FIAT; LSR5; TXLNGX; CXorf15  
NCBI Protein Information:gamma-taxilin
UniProt Protein Name:Gamma-taxilin
UniProt Synonym Protein Names:Environmental lipopolysaccharide-responding gene protein; Factor inhibiting ATF4-mediated transcription; FIAT; Lipopolysaccharide-specific response protein 5
Protein Family:Gamma-taxilin
UniProt Gene Name:TXLNG  
UniProt Entry Name:TXLNG_HUMAN
Anti-TXLNG Antibody (CAB15865)Western blot analysis of extracts of various cell lines, using TXLNG antibody (CAB15865) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 150s.
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