Cell Biology Antibodies 14
Anti-TSPY1 Antibody (CAB16992)
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- SKU:
- CAB16992
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TSPY1 Antibody |
| Antibody SKU: | CAB16992 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TSPY1 (NP_001071165.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TSPY1 (NP_001071165.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MRPE GSLT YRVP ERLR QGFC GVGR AAQA LVCA SAKE GTAF RMEA VQEG AAGV ESEQ AALG EEAV LLLD DIMA EVEV VAEE EGLV ERRE EAQR AQQA VPGP |
| Gene ID: | 7258 |
| Uniprot: | Q01534 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | TSPY1, CT78, DYS14, TSPY, pJA923 |
| Background: | The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of this gene are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | TSPY1: May be involved in sperm differentiation and proliferation. TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland. Belongs to the nucleosome assembly protein (NAP) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: Yp11.2 Molecular Function:protein binding Biological Process: cell proliferation; sex differentiation Disease: Gonadoblastoma |
| UniProt Code: | Q01534 |
| NCBI GenInfo Identifier: | 332278243 |
| NCBI Gene ID: | 728137 |
| NCBI Accession: | Q01534.4 |
| UniProt Secondary Accession: | Q01534,O00216, P09002, Q0VAD3, Q9UNN7, A6NJD2, |
| UniProt Related Accession: | P0CV98 |
| Molecular Weight: | 33,169 Da |
| NCBI Full Name: | Testis-specific Y-encoded protein 1 |
| NCBI Synonym Full Names: | testis specific protein, Y-linked 3 |
| NCBI Official Symbol: | TSPY3 |
| NCBI Official Synonym Symbols: | CT78 |
| NCBI Protein Information: | testis-specific Y-encoded protein 3 |
| UniProt Protein Name: | Testis-specific Y-encoded protein 1 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 78; CT78 |
| Protein Family: | Testis-specific Y-encoded protein |
| UniProt Gene Name: | TSPY1 |
| UniProt Entry Name: | TSPY1_HUMAN |
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