Cell Biology Antibodies 4

Anti-TSPAN31 Antibody (CAB14256)

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SKU:
CAB14256
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TSPAN31 Antibody
Antibody SKU:CAB14256
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 95-175 of human TSPAN31 (NP_005972.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat ovary
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 95-175 of human TSPAN31 (NP_005972.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SCLA INRS KQTD VINA SWWV MSNK TRDE LERS FDCC GLFN LTTL YQQD YDFC TAIC KSQS PTCQ MCGE KFLK HSDE ALKI L
Gene ID:6302
Uniprot:Q12999
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:23kDa
Observed MW:30kDa
Synonyms:TSPAN31, SAS
Background:The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.
UniProt Protein Function:TSPAN31: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: integral to plasma membrane; membrane

Biological Process: cell surface receptor linked signal transduction; positive regulation of cell proliferation

NCBI Summary:The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]
UniProt Code:Q12999
NCBI GenInfo Identifier:6174973
NCBI Gene ID:6302
NCBI Accession:Q12999.1
UniProt Secondary Accession:Q12999,O00577, Q53X76,
UniProt Related Accession:Q12999
Molecular Weight:23,053 Da
NCBI Full Name:Tetraspanin-31
NCBI Synonym Full Names:tetraspanin 31
NCBI Official Symbol:TSPAN31  
NCBI Official Synonym Symbols:SAS  
NCBI Protein Information:tetraspanin-31
UniProt Protein Name:Tetraspanin-31
UniProt Synonym Protein Names:Sarcoma-amplified sequence
Protein Family:Tetraspanin
UniProt Gene Name:TSPAN31  
UniProt Entry Name:TSN31_HUMAN
Anti-TSPAN31 Antibody (CAB14256)Western blot analysis of extracts of various cell lines, using TSPAN31 antibody (CAB14256) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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