Cell Biology Antibodies 13
Anti-TRPC7 Antibody (CAB17738)
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- SKU:
- CAB17738
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TRPC7 Antibody |
| Antibody SKU: | CAB17738 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-87MG, U-251MG, SH-SY5Y, A-549, 293T, Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 720-780 of human TRPC7 (NP_065122.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YLIM RIKM CLIK LCKS KAKS CEND LEMG MLNS KFKK TRYQ AGMR NSEN LTAN NTLS KPTR Y |
| Gene ID: | 57113 |
| Uniprot: | Q9HCX4 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 110kDa |
 | Western blot - TRPC7 Polyclonal Antibody (CAB17738) |
| Synonyms: | TRP7, TRPC7 |
| Background: |
| UniProt Protein Function: | TRPC7: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Channel, calcium Chromosomal Location of Human Ortholog: 5q31.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:calcium channel activity; protein binding; store-operated calcium channel activity Biological Process: cytosolic calcium ion homeostasis; manganese ion transport; platelet activation; single fertilization |
| UniProt Code: | Q9HCX4 |
| NCBI GenInfo Identifier: | 18202960 |
| NCBI Gene ID: | 57113 |
| NCBI Accession: | Q9HCX4.1 |
| UniProt Secondary Accession: | Q9HCX4,Q70T26, Q8IWP7, A1A4Z4, F5H5U9, |
| UniProt Related Accession: | Q9HCX4 |
| Molecular Weight: | 92,429 Da |
| NCBI Full Name: | Short transient receptor potential channel 7 |
| NCBI Synonym Full Names: | transient receptor potential cation channel subfamily C member 7 |
| NCBI Official Symbol: | TRPC7 |
| NCBI Official Synonym Symbols: | TRP7 |
| NCBI Protein Information: | short transient receptor potential channel 7 |
| UniProt Protein Name: | Short transient receptor potential channel 7 |
| UniProt Synonym Protein Names: | Transient receptor protein 7; TRP-7; hTRP7 |
| Protein Family: | Short transient receptor potential channel |
| UniProt Gene Name: | TRPC7 |
| UniProt Entry Name: | TRPC7_HUMAN |
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