Anti-TROY/TNFRSF19 Antibody (CAB19235)
- SKU:
- CAB19235
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TNFRSF19
- Synonyms:
- TAJ
- Synonyms:
- TAJ-alpha
- Synonyms:
- TRADE
- Synonyms:
- TROY
- Synonyms:
- TNF receptor superfamily member 19
- Research Area:
- Cell Death
Description
| Product Name: | TROY/TNFRSF19 Rabbit mAb |
| Product Code: | CAB19235 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | TNFRSF19, TAJ, TAJ-alpha, TRADE, TROY, TNF receptor superfamily member 19 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human TROY/TNFRSF19. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 22Rv1, Raji, U-251MG, Mouse lung, Mouse brain, Mouse spleen, Rat lung, Rat brain |
| Immunogen: | Recombinant protein of human TROY/TNFRSF19. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 55504 |
| Uniprot: | Q9NS68 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 46kDa |
| Observed MW: | 46KDa |
| UniProt Protein Function: | TNFRSF19: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 13q12.12 Cellular Component: plasma membrane Molecular Function:receptor activity Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; tissue development |
| NCBI Summary: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NS68 |
| NCBI GenInfo Identifier: | 325120959 |
| NCBI Gene ID: | 55504 |
| NCBI Accession: | NP_001191387.1 |
| UniProt Secondary Accession: | Q9NS68,Q9BXZ9, Q9BY00, Q9NZV2, A8KA09, A8KA26, B1AM40 B1AM41, B4E2I6, |
| UniProt Related Accession: | Q9NS68 |
| Molecular Weight: | 30,542 Da |
| NCBI Full Name: | tumor necrosis factor receptor superfamily member 19 isoform 2 |
| NCBI Synonym Full Names: | TNF receptor superfamily member 19 |
| NCBI Official Symbol: | TNFRSF19 |
| NCBI Official Synonym Symbols: | TAJ; TROY; TRADE; TAJ-alpha |
| NCBI Protein Information: | tumor necrosis factor receptor superfamily member 19 |
| UniProt Protein Name: | Tumor necrosis factor receptor superfamily member 19 |
| UniProt Synonym Protein Names: | TRADE; Toxicity and JNK inducer |
| UniProt Gene Name: | TNFRSF19 |
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