Epigenetics & Nuclear Signaling Antibodies 3

Anti-TRMT2B Antibody (CAB3509)

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SKU:
CAB3509
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-TRMT2B Antibody
Antibody SKU:CAB3509
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2B (NP_079193.2).
Application:WB IHC
Recommended Dilution:WB 1:1000 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:Raji, U-87MG, SW480, MCF7, NCI-H460
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2B (NP_079193.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAGL KRRV PLHS LRYF ISMV GLFS KPGL LPWY ARNP PGWS QLFL GTVC KGDF TRVI ATKC QKGQ KSQK KPSH LGPL DGSW QERL ADVV TPLW RLSY EEQL KVKF AAQK KILQ RLES YIQM LNGV SVTT AVPK SERL SCLL HPII PSPV INGY RNKS TFSV NRGP DGNP KTVG FYLG TWRD GNVV CVQS NHLK NIPE KHSQ VAQY YEVF LRQS PLEP CLVF HEGG YWRE LTVR TNSQ GHTM AIIT FHPQ KL
Gene ID:79979
Uniprot:Q96GJ1
Cellular Location:
Calculated MW:51kDa/55kDa/56kDa
Observed MW:45kDa
Synonyms:TRMT2B, CXorf34, dJ341D10.3
Background:This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.
UniProt Code:Q96GJ1
NCBI GenInfo Identifier:74762656
NCBI Gene ID:79979
NCBI Accession:Q96GJ1.1
UniProt Secondary Accession:Q96GJ1,Q5JPF0, Q5JVY6, Q96HU7, Q96IH9, Q9H9K2, A6NDG5 A6NEI9, A6NMG6,
UniProt Related Accession:Q96GJ1
Molecular Weight:504
NCBI Full Name:tRNA (uracil(54)-C(5))-methyltransferase homolog
NCBI Synonym Full Names:tRNA methyltransferase 2 homolog B (S. cerevisiae)
NCBI Official Symbol:TRMT2B  
NCBI Official Synonym Symbols:CXorf34; dJ341D10.3  
NCBI Protein Information:tRNA (uracil(54)-C(5))-methyltransferase homolog; tRNA (uracil(54)-C(5))-methyltransferase homolog; TRM2 homolog; TRM2 tRNA methyltransferase 2 homolog B; tRNA (uracil-5-)-methyltransferase homolog
UniProt Protein Name:tRNA (uracil(54)-C(5))-methyltransferase homolog
UniProt Synonym Protein Names:TRM2 homolog
Protein Family:tRNA
UniProt Gene Name:TRMT2B  
UniProt Entry Name:TRM2_HUMAN
Anti-TRMT2B Antibody (CAB3509)Western blot analysis of extracts of various cell lines, using TRMT2B antibody (CAB3509) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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