Signal Transduction Antibodies 2
Anti-TRIM62 Antibody (CAB15855)
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- SKU:
- CAB15855
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-TRIM62 Antibody |
| Antibody SKU: | CAB15855 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_060677.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-431, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_060677.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HEQH QVTG IDDA FDEL QREL KDQL QALQ DSER EHTE ALQL LKRQ LAET KSST KSLR TTIG EAFE RLHR LLRE RQKA MLEE LEAD TART LTDI EQKV QRYS QQLR KVQE GAQI LQER LAET DRHT FLAG VASL SERL KGKI HETN LTYE DFPT SKYT GPLQ Y |
| Gene ID: | 55223 |
| Uniprot: | Q9BVG3 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 40kDa/54kDa |
| Observed MW: | 54kDa |
| Synonyms: | TRIM62, DEAR1 |
| Background: |
| UniProt Protein Function: | TRIM62: Belongs to the TRIM/RBCC family. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 1p35.1 Cellular Component: cytoplasm; cytosol Molecular Function:ubiquitin-protein ligase activity Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; regulation of virion penetration into host cell |
| UniProt Code: | Q9BVG3 |
| NCBI GenInfo Identifier: | 74752380 |
| NCBI Gene ID: | 55223 |
| NCBI Accession: | Q9BVG3.1 |
| UniProt Secondary Accession: | Q9BVG3,Q9NVG0, B3KVH5, B4DTE4, D3DPR1, |
| UniProt Related Accession: | Q9BVG3 |
| Molecular Weight: | 40,490 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase TRIM62 |
| NCBI Synonym Full Names: | tripartite motif containing 62 |
| NCBI Official Symbol: | TRIM62 |
| NCBI Official Synonym Symbols: | DEAR1 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM62 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM62 |
| UniProt Synonym Protein Names: | Tripartite motif-containing protein 62 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | TRIM62 |
| UniProt Entry Name: | TRI62_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TRIM62 antibody (CAB15855) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded Human colon using TRIM62 Rabbit pAb (CAB15855) at dilution of 1:100 (40x lens). |
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