Cell Biology Antibodies 14
Anti-TRIM56 Antibody (CAB18109)
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- SKU:
- CAB18109
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TRIM56 Antibody |
| Antibody SKU: | CAB18109 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human TRIM56. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human TRIM56. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 81844 |
| Uniprot: | Q9BRZ2 |
| Cellular Location: | |
| Calculated MW: | 81kDa |
| Observed MW: | Refer to figures |
| Synonyms: | RNF109, TRIM56 |
| Background: |
| UniProt Protein Function: | TRIM56: E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA. Belongs to the TRIM/RBCC family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; Ubiquitin conjugating system; EC 6.3.2.- Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: cytoplasm; cytosol Molecular Function:ubiquitin-protein ligase activity Biological Process: defense response to virus; interferon-beta production; regulation of interferon type I production |
| UniProt Code: | Q9BRZ2 |
| NCBI GenInfo Identifier: | 56749788 |
| NCBI Gene ID: | 81844 |
| NCBI Accession: | Q9BRZ2.3 |
| UniProt Secondary Accession: | Q9BRZ2,Q6PJS5, Q86VT6, Q8N2H8, Q8NAC0, Q9H031, |
| UniProt Related Accession: | Q9BRZ2 |
| Molecular Weight: | 29,185 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase TRIM56 |
| NCBI Synonym Full Names: | tripartite motif containing 56 |
| NCBI Official Symbol: | TRIM56 |
| NCBI Official Synonym Symbols: | RNF109 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM56 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM56 |
| UniProt Synonym Protein Names: | RING finger protein 109; Tripartite motif-containing protein 56 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | TRIM56 |
| UniProt Entry Name: | TRI56_HUMAN |
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