Cell Death Antibodies 2

Anti-TRIM39 Antibody (CAB9977)

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SKU:
CAB9977
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death

Description

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Antibody Name:Anti-TRIM39 Antibody
Antibody SKU:CAB9977
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TRIM39 (NP_067076.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:293T, LO2, K-562, SW480, MCF7
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TRIM39 (NP_067076.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LVLS EDRK SVKF VETR LRDL PDTP RRFT FYPC VLAT EGFT SGRH YWEV EVGD KTHW AVGV CRDS VSRK GELT PLPE TGYW RVRL WNGD KYAA TTTP FTPL H
Gene ID:56658
Uniprot:Q9HCM9
Cellular Location:Cytoplasm, Mitochondrion, cytosol
Calculated MW:56kDa/59kDa
Observed MW:59kDa
Synonyms:TRIM39, RNF23, TFP, TRIM39B
Background:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms.
UniProt Protein Function:TRIM39: E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: cytosol; mitochondrion

Molecular Function:identical protein binding; protein binding

NCBI Summary:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:Q9HCM9
NCBI GenInfo Identifier:56405385
NCBI Gene ID:56658
NCBI Accession:Q9HCM9.2
UniProt Secondary Accession:Q9HCM9,Q5STG3, Q5STG4, Q76BL3, Q8IYT9, Q96IB6,
UniProt Related Accession:Q9HCM9
Molecular Weight:60kDa
NCBI Full Name:E3 ubiquitin-protein ligase TRIM39
NCBI Synonym Full Names:tripartite motif containing 39
NCBI Official Symbol:TRIM39  
NCBI Official Synonym Symbols:TFP; RNF23; TRIM39B  
NCBI Protein Information:E3 ubiquitin-protein ligase TRIM39
UniProt Protein Name:E3 ubiquitin-protein ligase TRIM39
UniProt Synonym Protein Names:RING finger protein 23; RING-type E3 ubiquitin transferase TRIM39Curated; Testis-abundant finger protein; Tripartite motif-containing protein 39
Protein Family:E3 ubiquitin-protein ligase
UniProt Gene Name:TRIM39  
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