Cell Biology Antibodies 16

Anti-TRIM31 Antibody (CAB10639)

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SKU:
CAB10639
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TRIM31 Antibody
Antibody SKU:CAB10639
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 186-425 of human TRIM31 (NP_008959.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:HT-29, Mouse large intestine, Mouse small intestine
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 186-425 of human TRIM31 (NP_008959.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ELLH QVLE EEKN FLLS RIYW LGHE GTEA GKHY VAST EPQL NDLK KLVD SLKT KQNM PPRQ LLED IKVV LCRS EEFQ FLNP TPVP LELE KKLS EAKS RHDS ITGS LKKF KDQL QADR KKDE NRFF KSMN KNDM KSWG LLQK NNHK MNKT SEPG SSSA GGRT TSGP PNHH SSAP SHSL FRAS SAGK VTFP VCLL ASYD EISG QGAS SQDT KTFD VALS EELH AALS EWLT AIRA WFCE VPSS
Gene ID:11074
Uniprot:Q9BZY9
Cellular Location:Cytoplasm, Mitochondrion
Calculated MW:30kDa/48kDa
Observed MW:48kDa
Anti-TRIM31 AntibodyWestern blot - TRIM31 Rabbit pAb (CAB10639)
Synonyms:TRIM31, C6orf13, HCG1, HCGI, RNF
Background:This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:TRIM31: Regulator of Src-induced anchorage independent cell growth. May have E3 ubiquitin-protein ligase activity. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 6.3.2.-; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: cytosol

Molecular Function:protein binding

Biological Process: innate immune response; negative regulation of viral transcription; negative regulation of virion penetration into host cell; positive regulation of transcription factor activity

NCBI Summary:This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Code:Q9BZY9
NCBI GenInfo Identifier:68068082
NCBI Gene ID:11074
NCBI Accession:Q9BZY9.2
UniProt Secondary Accession:Q9BZY9,Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4 Q96AP8, Q99579, Q9BZY8, A6NLX6, A9R9Q4,
UniProt Related Accession:Q9BZY9
Molecular Weight:30,831 Da
NCBI Full Name:E3 ubiquitin-protein ligase TRIM31
NCBI Synonym Full Names:tripartite motif containing 31
NCBI Official Symbol:TRIM31  
NCBI Official Synonym Symbols:RNF; HCG1; HCGI; C6orf13  
NCBI Protein Information:E3 ubiquitin-protein ligase TRIM31
UniProt Protein Name:E3 ubiquitin-protein ligase TRIM31
UniProt Synonym Protein Names:Tripartite motif-containing protein 31
Protein Family:E3 ubiquitin-protein ligase
UniProt Gene Name:TRIM31  
UniProt Entry Name:TRI31_HUMAN
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