Immunology Antibodies 2
Anti-TRIM29 Antibody (CAB7508)
- SKU:
- CAB7508
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Antibody Name: | Anti-TRIM29 Antibody |
Antibody SKU: | CAB7508 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 309-588 of human TRIM29 (NP_036233.2). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | Mouse thymus |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 309-588 of human TRIM29 (NP_036233.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | ILEQ NFRD LVRD LEKQ KEEV RAAL EQRE QDAV DQVK VIMD ALDE RAKV LHED KQTR EQLH SISD SVLF LQEF GALM SNYS LPPP LPTY HVLL EGEG LGQS LGNF KDDL LNVC MRHV EKMC KADL SRNF IERN HMEN GGDH RYVN NYTN SFGG EWSA PDTM KRYS MYLT PKGG VRTS YQPS SPGR FTKE TTQK NFNN LYGT KGNY TSRV WEYS SSIQ NSDN DLPV VQGS SSFS LKGY PSLM RSQS PKAQ PQTW KSGK QTML SHYR PFYV NKGN GIGS NEAP |
Gene ID: | 23650 |
Uniprot: | Q14134 |
Cellular Location: | Cytoplasm |
Calculated MW: | 63kDa/65kDa |
Observed MW: | 68kDa |
Synonyms: | TRIM29, ATDC |
Background: | The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. |
UniProt Protein Function: | TRIM29: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. Interacts with VIM and HINT1. Expressed in placenta, prostate and thymus. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: nucleoplasm; intermediate filament cytoskeleton; cytoplasm Molecular Function:protein binding; zinc ion binding; p53 binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14134 |
NCBI GenInfo Identifier: | 116242825 |
NCBI Gene ID: | 23650 |
NCBI Accession: | Q14134.2 |
UniProt Secondary Accession: | Q14134,Q8R2Q0, |
UniProt Related Accession: | Q14134 |
Molecular Weight: | 588 |
NCBI Full Name: | Tripartite motif-containing protein 29 |
NCBI Synonym Full Names: | tripartite motif containing 29 |
NCBI Official Symbol: | TRIM29 |
NCBI Official Synonym Symbols: | ATDC |
NCBI Protein Information: | tripartite motif-containing protein 29; tripartite motif-containing 29; tripartite motif protein TRIM29; ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein |
UniProt Protein Name: | Tripartite motif-containing protein 29 |
UniProt Synonym Protein Names: | Ataxia telangiectasia group D-associated protein |
Protein Family: | Tripartite motif-containing protein |
UniProt Gene Name: | TRIM29 |
UniProt Entry Name: | TRI29_HUMAN |
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