Immunology Antibodies 1

Anti-TRIM26 Antibody (CAB15332)

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SKU:
CAB15332
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-TRIM26 Antibody
Antibody SKU:CAB15332
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRIM26 (NP_001229712.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Rat
Positive Samples:Jurkat, Rat thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRIM26 (NP_001229712.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATS APLR SLEE EVTC SICL DYLR DPVT IDCG HVFC RSCT TDVR PISG SRPV CPLC KKPF KKEN IRPV WQLA SLVE NIER LKVD KGRQ PGEV TREQ QDAK LCER HREK LHYY CEDD GKLL CVMC RESR EHRP HTAV LMEK AAQP HREK ILNH LSTL RRDR DKIQ GFQA KGEA DILA ALKK LQDQ RQYI VAEF EQGH QFLR EREE HLLE QLAK LEQE LTEG REKF KSRG VGEL ARLA LVIS ELEG KAQQ PAAE LMQD TRDF LNRY PRKK FWVG KPIA RVVK KKTG EFSD KLLS LQRG LREF
Gene ID:7726
Uniprot:Q12899
Cellular Location:
Calculated MW:62kDa
Observed MW:62kDa
Synonyms:TRIM26, AFP, RNF95, ZNF173
Background:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
UniProt Protein Function:TRIM26: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]
UniProt Protein Details:

Protein type:DNA-binding; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: cytosol

Molecular Function:protein binding

Biological Process: innate immune response; negative regulation of virion penetration into host cell; positive regulation of transcription factor activity

NCBI Summary:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]
UniProt Code:Q12899
NCBI GenInfo Identifier:17380344
NCBI Gene ID:7726
NCBI Accession:Q12899.1
UniProt Secondary Accession:Q12899,Q5SRL2, A6NG96,
UniProt Related Accession:Q12899
Molecular Weight:62,166 Da
NCBI Full Name:Tripartite motif-containing protein 26
NCBI Synonym Full Names:tripartite motif containing 26
NCBI Official Symbol:TRIM26  
NCBI Official Synonym Symbols:AFP; RNF95; ZNF173  
NCBI Protein Information:tripartite motif-containing protein 26
UniProt Protein Name:Tripartite motif-containing protein 26
UniProt Synonym Protein Names:Acid finger protein; AFP; RING finger protein 95; Zinc finger protein 173
Protein Family:Tripartite motif-containing protein
UniProt Gene Name:TRIM26  
UniProt Entry Name:TRI26_HUMAN
Anti-TRIM26 Antibody (CAB15332)Western blot analysis of extracts of various cell lines, using TRIM26 antibody (CAB15332) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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