Cell Biology Antibodies 13

Anti-TRIM16 Antibody (CAB17619)

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SKU:
CAB17619
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TRIM16 Antibody
Antibody SKU:CAB17619
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TRIM16 (NP_006461.3).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse lung, Mouse thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TRIM16 (NP_006461.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAEL DLMA PGPL PRAT AQPP APLS PDSG SPSP DSGS ASPV EEED VGSS EKLG RETE EQDS DSAE QGDP AGEG KEVL CDFC LDDT RRVK AVKS CLTC MVNY CEEH LQPH QVNI KLQS HLLT EPVK DHNW RYCP AHHS PLSA FCCP DQQC ICQD CCQE HSGH TIVS LDAA RRDK EAEL QCTQ LDLE RKLK LNEN AISR LQAN QKSV LVSV SE
Gene ID:10626
Uniprot:O95361
Cellular Location:
Calculated MW:
Observed MW:64kDa
Anti-TRIM16 Antibody (CAB17619)Western blot - TRIM16 Polyclonal Antibody (CAB17619)
Synonyms:EBBP, TRIM16
Background:The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017]
UniProt Protein Function:TRIM16: May play a role in the regulation of keratinocyte differentiation. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: cytoplasm; PML body

Molecular Function:DNA binding; interleukin-1 binding; NACHT domain binding; protein binding

Biological Process: positive regulation of interleukin-1 beta secretion; positive regulation of keratinocyte differentiation; positive regulation of retinoic acid receptor signaling pathway; positive regulation of transcription, DNA-dependent; response to organophosphorus; response to retinoic acid

NCBI Summary:This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008]
UniProt Code:O95361
NCBI GenInfo Identifier:145559535
NCBI Gene ID:10626
NCBI Accession:O95361.3
UniProt Secondary Accession:O95361,Q6IAL8, Q7Z6I2, Q96BE8, Q96J43,
UniProt Related Accession:O95361
Molecular Weight:40,370 Da
NCBI Full Name:Tripartite motif-containing protein 16
NCBI Synonym Full Names:tripartite motif containing 16
NCBI Official Symbol:TRIM16  
NCBI Official Synonym Symbols:EBBP  
NCBI Protein Information:tripartite motif-containing protein 16
UniProt Protein Name:Tripartite motif-containing protein 16
UniProt Synonym Protein Names:Estrogen-responsive B box protein
Protein Family:Tripartite motif-containing protein
UniProt Gene Name:TRIM16  
UniProt Entry Name:TRI16_HUMAN
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