Cell Biology Antibodies 2

Anti-TRIM15 Antibody (CAB11730)

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SKU:
CAB11730
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TRIM15 Antibody
Antibody SKU:CAB11730
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human TRIM15 (NP_150232.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:Jurkat, HT-29, 293T, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human TRIM15 (NP_150232.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPAT PSLK VVHE LPAC TLCA GPLE DAVT IPCG HTFC RLCL PALS QMGA QSSG KILL CPLC QEEE QAET PMAP VPLG PLGE TYCE EHGE KIYF FCEN DAEF LCVF CREG PTHQ AHTV GFLD EAIQ PYRD RLRS RLEA LSTE RDEI EDVK CQED QKLQ VLLT QIES KKHQ VETA FERL QQEL EQQR CLLL ARLR ELEQ QIWK ERDE YITK VSEE VTRL GAQV KELE EKCQ QPAS ELLQ DVRV NQSR CEMK TFVS PEAI SPDL VKKI RDFH RKIL TLPE MMRM FSEN LAHH LEID SGVI TLDP QTAS RSLV LSED RKSV RYTR QKKS LPDS PL
Gene ID:89870
Uniprot:Q9C019
Cellular Location:
Calculated MW:12kDa/52kDa
Observed MW:52kDa
Synonyms:TRIM15, RNF93, ZNF178, ZNFB7
Background:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
UniProt Protein Function:TRIM15: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Cell development/differentiation; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6p22.1

Molecular Function:protein binding

Biological Process: activation of NF-kappaB transcription factor; innate immune response; mesodermal cell fate determination; positive regulation of interferon type I production; positive regulation of transcription factor activity

NCBI Summary:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q9C019
NCBI GenInfo Identifier:25009482
NCBI Gene ID:89870
NCBI Accession:Q9C019.1
UniProt Secondary Accession:Q9C019,O95604, Q8IUX9, Q9C018, A2BEC9,
UniProt Related Accession:Q9C019
Molecular Weight:52kDa
NCBI Full Name:Tripartite motif-containing protein 15
NCBI Synonym Full Names:tripartite motif containing 15
NCBI Official Symbol:TRIM15  
NCBI Official Synonym Symbols:RNF93; ZNFB7; ZNF178  
NCBI Protein Information:tripartite motif-containing protein 15
UniProt Protein Name:Tripartite motif-containing protein 15
UniProt Synonym Protein Names:RING finger protein 93; Zinc finger protein 178; Zinc finger protein B7
Protein Family:Tripartite motif-containing protein
UniProt Gene Name:TRIM15  
Anti-TRIM15 Antibody (CAB11730)Western blot analysis of extracts of various cell lines, using TRIM15 antibody (CAB11730) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-TRIM15 Antibody (CAB11730)Immunohistochemistry of paraffin-embedded rat liver using TRIM15 antibody (CAB11730) at dilution of 1:100 (40x lens).
Anti-TRIM15 Antibody (CAB11730)Immunohistochemistry of paraffin-embedded human vermiform appendix using TRIM15 antibody (CAB11730) at dilution of 1:100 (40x lens).
Anti-TRIM15 Antibody (CAB11730)Immunohistochemistry of paraffin-embedded human uterine cancer using TRIM15 antibody (CAB11730) at dilution of 1:100 (40x lens).
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