Cell Death Antibodies 2
Anti-TRIAP1 Antibody (CAB7313)
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- SKU:
- CAB7313
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-TRIAP1 Antibody |
| Antibody SKU: | CAB7313 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNSV GEAC TDMK REYD QCFN RWFA EKFL KGDS SGDP CTDL FKRY QQCV QKAI KEKE IPIE GLEF MGHG KEKP ENSS |
| Gene ID: | 51499 |
| Uniprot: | O43715 |
| Cellular Location: | Cytoplasm, Mitochondrion, Mitochondrion intermembrane space, perinuclear region |
| Calculated MW: | 8kDa |
| Observed MW: | Refer to figures |
| Synonyms: | TRIAP1, HSPC132, MDM35, P53CSV, WF-1 |
| Background: |
| UniProt Protein Function: | TRIAP1: Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. Belongs to the TRIAP1/MDM35 family. |
| UniProt Protein Details: | Protein type:Apoptosis; Mitochondrial; Inhibitor Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: protein complex; mitochondrion; perinuclear region of cytoplasm; mitochondrial intermembrane space Molecular Function:protein binding; p53 binding Biological Process: DNA damage response, signal transduction by p53 class mediator; positive regulation of transcription from RNA polymerase II promoter; phospholipid transport; negative regulation of caspase activity; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; negative regulation of apoptosis |
| UniProt Code: | O43715 |
| NCBI GenInfo Identifier: | 9910620 |
| NCBI Gene ID: | 51499 |
| NCBI Accession: | O43715.1 |
| UniProt Secondary Accession: | O43715,Q5RKS5, Q6LCA7, B2R4Z7, |
| UniProt Related Accession: | O43715 |
| Molecular Weight: | 76 |
| NCBI Full Name: | TP53-regulated inhibitor of apoptosis 1 |
| NCBI Synonym Full Names: | TP53 regulated inhibitor of apoptosis 1 |
| NCBI Official Symbol: | TRIAP1 |
| NCBI Official Synonym Symbols: | WF-1; MDM35; P53CSV; HSPC132 |
| NCBI Protein Information: | TP53-regulated inhibitor of apoptosis 1; protein 15E1.1; p53-inducible cell-survival factor; mitochondrial distribution and morphology 35 homolog |
| UniProt Protein Name: | TP53-regulated inhibitor of apoptosis 1 |
| UniProt Synonym Protein Names: | Protein 15E1.1; WF-1; p53-inducible cell-survival factor; p53CSV |
| Protein Family: | TP53-regulated inhibitor of apoptosis |
| UniProt Gene Name: | TRIAP1 |
| UniProt Entry Name: | TRIA1_HUMAN |
 | Immunofluorescence analysis of MCF-7 cells using TRIAP1 antibody (CAB7313). Blue: DAPI for nuclear staining. |
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