Cell Biology Antibodies 1
Anti-TREML1 Antibody (CAB10414)
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- SKU:
- CAB10414
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TREML1 Antibody |
| Antibody SKU: | CAB10414 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse liver, Mouse lung, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QGIV GSLP EVLQ APVG SSIL VQCH YRLQ DVKA QKVW CRFL PEGC QPLV SSAV DRRA PAGR RTFL TDLG GGLL QVEM VTLQ EEDA GEYG CMVD GARG PQIL HRVS LNIL PPEE EEET HKIG SLAE NAFS DPAG SANP LEPS QDEK SIP |
| Gene ID: | 340205 |
| Uniprot: | Q86YW5 |
| Cellular Location: | Cell membrane, Cytoplasm, Single-pass type I membrane protein |
| Calculated MW: | 20kDa/21kDa/32kDa |
| Observed MW: | 33kDa |
| Synonyms: | TREML1, GLTL1825, PRO3438, TLT-1, TLT1, dJ238O23.3 |
| Background: | This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants |
| UniProt Protein Function: | TREML1: Cell surface receptor that may play a role in the innate and adaptive immune response. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: plasma membrane Biological Process: regulation of immune response |
| NCBI Summary: | This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q86YW5 |
| NCBI GenInfo Identifier: | 116256098 |
| NCBI Gene ID: | 340205 |
| NCBI Accession: | Q86YW5.2 |
| UniProt Secondary Accession: | Q86YW5,Q496B3, Q8IWY1, Q8IWY2, |
| UniProt Related Accession: | Q86YW5 |
| Molecular Weight: | 33kDa |
| NCBI Full Name: | Trem-like transcript 1 protein |
| NCBI Synonym Full Names: | triggering receptor expressed on myeloid cells like 1 |
| NCBI Official Symbol: | TREML1 |
| NCBI Official Synonym Symbols: | TLT1; TLT-1; PRO3438; GLTL1825; dJ238O23.3 |
| NCBI Protein Information: | trem-like transcript 1 protein |
| UniProt Protein Name: | Trem-like transcript 1 protein |
| UniProt Synonym Protein Names: | Triggering receptor expressed on myeloid cells-like protein 1 |
| Protein Family: | Trem-like transcript 1 protein |
| UniProt Gene Name: | TREML1 |
 | Western blot analysis of extracts of various cell lines, using TREML1 antibody (CAB10414) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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