Cell Biology Antibodies 1

Anti-TREML1 Antibody (CAB10414)

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SKU:
CAB10414

Description

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Antibody Name:Anti-TREML1 Antibody
Antibody SKU:CAB10414
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver, Mouse lung, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QGIV GSLP EVLQ APVG SSIL VQCH YRLQ DVKA QKVW CRFL PEGC QPLV SSAV DRRA PAGR RTFL TDLG GGLL QVEM VTLQ EEDA GEYG CMVD GARG PQIL HRVS LNIL PPEE EEET HKIG SLAE NAFS DPAG SANP LEPS QDEK SIP
Gene ID:340205
Uniprot:Q86YW5
Cellular Location:Cell membrane, Cytoplasm, Single-pass type I membrane protein
Calculated MW:20kDa/21kDa/32kDa
Observed MW:33kDa
Synonyms:TREML1, GLTL1825, PRO3438, TLT-1, TLT1, dJ238O23.3
Background:This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants
UniProt Protein Function:TREML1: Cell surface receptor that may play a role in the innate and adaptive immune response. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: plasma membrane

Biological Process: regulation of immune response

NCBI Summary:This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]
UniProt Code:Q86YW5
NCBI GenInfo Identifier:116256098
NCBI Gene ID:340205
NCBI Accession:Q86YW5.2
UniProt Secondary Accession:Q86YW5,Q496B3, Q8IWY1, Q8IWY2,
UniProt Related Accession:Q86YW5
Molecular Weight:33kDa
NCBI Full Name:Trem-like transcript 1 protein
NCBI Synonym Full Names:triggering receptor expressed on myeloid cells like 1
NCBI Official Symbol:TREML1  
NCBI Official Synonym Symbols:TLT1; TLT-1; PRO3438; GLTL1825; dJ238O23.3  
NCBI Protein Information:trem-like transcript 1 protein
UniProt Protein Name:Trem-like transcript 1 protein
UniProt Synonym Protein Names:Triggering receptor expressed on myeloid cells-like protein 1
Protein Family:Trem-like transcript 1 protein
UniProt Gene Name:TREML1  
Anti-TREML1 Antibody (CAB10414)Western blot analysis of extracts of various cell lines, using TREML1 antibody (CAB10414) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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Additional Information

Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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