Cell Biology Antibodies 10

Anti-TRAPPC10 Antibody (CAB6777)

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SKU:
CAB6777
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TRAPPC10 Antibody
Antibody SKU:CAB6777
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TRAPPC10 (NP_003265.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse kidney, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TRAPPC10 (NP_003265.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MDAS EEPL PPVI YTME NKPI VTCA GDQN LFTS VYPT LSQQ LPRE PMEW RRSY GRAP KMIH LESN FVQF KEEL LPKE GNKA LLTF PFLH IYWT ECCD TEVY KATV KDDL TKWQ NVLK AHSS VDWL IVIV ENDA KKKN KTNI LPRT SIVD KIRN DFCN KQSD RCVV LSDP LKDS SRTQ ESWN AFLT KLRT LLLM SFTK NLGK FEDD MRTL REKR TEPG WSFC EYFM VQEE LAFV FEML QQFE DALV QYDE LDAL FSQY VVNF
Gene ID:7109
Uniprot:P48553
Cellular Location:Golgi apparatus, cis-Golgi network
Calculated MW:32kDa/142kDa
Observed MW:112kDa
Synonyms:TRAPPC10, EHOC-1, EHOC1, GT334, TMEM1, TRS130, TRS30
Background:The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1.
UniProt Protein Function:EHOC-1: a transport protein that may play role in vesicular transport from endoplasmic reticulum to Golgi. Part of the multisubunit TRAPP (transport protein particle) complex. Localizes in cis-Golgi complexes.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: integral to membrane

Molecular Function:protein binding; sodium ion transmembrane transporter activity

Biological Process: intra-Golgi vesicle-mediated transport; sodium ion transport

NCBI Summary:The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq, Jul 2008]
UniProt Code:P48553
NCBI GenInfo Identifier:12644285
NCBI Gene ID:7109
NCBI Accession:P48553.2
UniProt Secondary Accession:P48553,Q3MIR2, Q86SI7, Q9UMD4, Q9Y4L3,
UniProt Related Accession:P48553
Molecular Weight:142kDa
NCBI Full Name:Trafficking protein particle complex subunit 10
NCBI Synonym Full Names:trafficking protein particle complex 10
NCBI Official Symbol:TRAPPC10  
NCBI Official Synonym Symbols:EHOC1; GT334; TMEM1; TRS30; EHOC-1; TRS130  
NCBI Protein Information:trafficking protein particle complex subunit 10; TRAPP subunit TMEM1; TRAPP 130 kDa subunit; transmembrane protein 1; transport protein particle subunit TMEM1; epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; trafficking protein particle complex subunit 130; trafficking protein particle complex subunit TMEM1
UniProt Protein Name:Trafficking protein particle complex subunit 10
UniProt Synonym Protein Names:Epilepsy holoprosencephaly candidate 1 protein; EHOC-1; Protein GT334; Trafficking protein particle complex subunit TMEM1; Transport protein particle subunit TMEM1; TRAPP subunit TMEM1
Protein Family:Trafficking protein particle complex
UniProt Gene Name:TRAPPC10  
UniProt Entry Name:TPC10_HUMAN
Anti-TRAPPC10 Antibody (CAB6777)Western blot analysis of extracts of various cell lines, using TRAPPC10 antibody (CAB6777) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15min.
Anti-TRAPPC10 Antibody (CAB6777)Immunofluorescence analysis of U2OS cells using TRAPPC10 antibody (CAB6777). Blue: DAPI for nuclear staining.
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