Immunology Antibodies 1

Anti-TRAFD1 Antibody (CAB13073)

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SKU:
CAB13073
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology

Description

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Antibody Name:Anti-TRAFD1 Antibody
Antibody SKU:CAB13073
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TRAFD1 (NP_006691.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human
Positive Samples:A375, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TRAFD1 (NP_006691.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAEF LDDQ ETRL CDNC KKEI PVFN FTIH EIHC QRNI GMCP TCKE PFPK SDME THMA AEHC QVTC KCNK KLEK RLLK KHEE TECP LRLA VCQH CDLE LSIL KLKE HEDY CGAR TELC GNCG RNVL VKDL KTHP EVCG REGE EKRN EVAI PPNA YDES WGQD GIWI ASQL LRQI EALD PPMR LPRR PLRA FESD VFHN RTTN QRNI TAQV SIQN NLFE EQER QERN RGQQ PPKE GGEE SANL DFML ALSL QNEG QASS VAEQ
Gene ID:10906
Uniprot:O14545
Cellular Location:
Calculated MW:19kDa/64kDa
Observed MW:78kDa
Synonyms:TRAFD1, FLN29
Background:
UniProt Protein Function:FLN29: a protein of unknown function. Contains a C2H2 zinc finger frequently associated with DNA binding.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 12q

Molecular Function:protein binding; metal ion binding

Biological Process: negative regulation of innate immune response; response to cytokine stimulus

NCBI Summary:The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009]
UniProt Code:O14545
NCBI GenInfo Identifier:74754309
NCBI Gene ID:10906
NCBI Accession:O14545.1
UniProt Secondary Accession:O14545,A8K5L6, B4DI89,
UniProt Related Accession:O14545
Molecular Weight:19,034 Da
NCBI Full Name:TRAF-type zinc finger domain-containing protein 1
NCBI Synonym Full Names:TRAF-type zinc finger domain containing 1
NCBI Official Symbol:TRAFD1  
NCBI Official Synonym Symbols:FLN29  
NCBI Protein Information:TRAF-type zinc finger domain-containing protein 1; FLN29 gene product
UniProt Protein Name:TRAF-type zinc finger domain-containing protein 1
UniProt Synonym Protein Names:Protein FLN29
Protein Family:TRAF-type zinc finger domain-containing protein
UniProt Gene Name:TRAFD1  
UniProt Entry Name:TRAD1_HUMAN
Anti-TRAFD1 Antibody (CAB13073)Western blot analysis of extracts of various cell lines, using TRAFD1 antibody (CAB13073) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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