Signal Transduction Antibodies 2
Anti-TRAF3IP3 Antibody (CAB15899)
- SKU:
- CAB15899
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Antibody Name: | Anti-TRAF3IP3 Antibody |
Antibody SKU: | CAB15899 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-530 of human TRAF3IP3 (NP_079504.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse, Rat |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-530 of human TRAF3IP3 (NP_079504.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | VLEE KMNA EQQL QSTQ RSLA LAEQ KCEE WRSQ YEAL KEDW RTLG TQHR ELES QLHV LQSK LQGA DSRD LQMN QALR FLEN EHQQ LQAK IECL QGDR DLCS LDTQ DLQD QLKR SEAE KLTL VTRV QQLQ GLLQ NQSL QLQE QEKL LTKK DQAL PVWS PKSF PNEV EPEG TGKE KDWD LRDQ LQKK TLQL QAKE KECR ELHS ELDN LSDE YLSC LRKL QHCR EELN QSQQ LPPR RQCG RWLP V |
Gene ID: | 80342 |
Uniprot: | Q9Y228 |
Cellular Location: | Membrane, Single-pass type IV membrane protein |
Calculated MW: | 40kDa/61kDa/63kDa |
Observed MW: | Refer to figures |
Synonyms: | TRAF3IP3, T3JAM |
Background: | The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | TRAF3IP3: May function as an adapter molecule that regulates TRAF3-mediated JNK activation. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q32 Molecular Function:protein binding |
NCBI Summary: | The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
UniProt Code: | Q9Y228 |
NCBI GenInfo Identifier: | 88984949 |
NCBI Gene ID: | 80342 |
NCBI Accession: | Q9Y228.2 |
UniProt Secondary Accession: | Q9Y228,Q2YDB5, Q4VY06, Q7Z706, A1L464, A6NIU9, |
UniProt Related Accession: | Q9Y228 |
Molecular Weight: | 40,674 Da |
NCBI Full Name: | TRAF3-interacting JNK-activating modulator |
NCBI Synonym Full Names: | TRAF3 interacting protein 3 |
NCBI Official Symbol: | TRAF3IP3 |
NCBI Official Synonym Symbols: | T3JAM |
NCBI Protein Information: | TRAF3-interacting JNK-activating modulator |
UniProt Protein Name: | TRAF3-interacting JNK-activating modulator |
UniProt Synonym Protein Names: | TRAF3-interacting protein 3 |
Protein Family: | TRAF3-interacting JNK-activating modulator |
UniProt Gene Name: | TRAF3IP3 |
UniProt Entry Name: | T3JAM_HUMAN |
View AllClose